Xenotransplantation of Stem/Progenitor Cells from Human Fetal Brain to Adult Rats with Spinal Trauma

被引:0
|
作者
G. A. Stepanov
D. O. Karpenko
M. A. Aleksandrova
O. V. Podgornyi
R. A. Poltavtseva
A. V. Pevishchin
M. V. Marey
G. T. Sukhikh
机构
[1] Central Institute of Traumatology and Orthopedics,Russian Academy of Sciences
[2] N. K. Kol'tsov Institute of Developmental Biology,Russian Academy of Sciences
[3] Institute of Ecological and Evolutional Problems,Center for Obstetrics, Gynecology, and Perinatology
[4] Russian Academy of Medical Sciences,undefined
关键词
human neural stem/progenitor cells; xenotransplantation; spinal cord; immunohistochemistry;
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学科分类号
摘要
In vitro grown neural stem cells from human fetal brain were transplanted to adult rats with spinal trauma. The spinal cord was examined morphologically using histological and immunohistochemical methods on days 5, 15, 30, and 110. Human neural stem/progenitor cells were viable, migrated, and differentiated into neurons and glia in the traumatized spinal cord in adult rats.
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页码:397 / 400
页数:3
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