Importance of oestrogen receptors to preserve functional β-cell mass in diabetes

被引：0
作者：
Joseph P. Tiano
Franck Mauvais-Jarvis
机构：
[1] Feinberg School of Medicine,Division of Endocrinology
[2] Metabolism and Molecular Medicine and Comprehensive Center on Obesity,undefined
[3] Northwestern University,undefined
来源：
Nature Reviews Endocrinology | 2012年 / 8卷
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摘要：
This Review describes developments in the role of estrogen receptors (ERs) in islet insulin biosynthesis and secretion, lipid homeostasis and survival. Moreover, the authors discuss why and how enhancing ER action in β cells without the undesirable effect of general estrogen therapy is a therapeutic avenue to preserve functional β-cell mass in patients with diabetes mellitus.
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页码：342 / 351
页数：9
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