Prognostic Role of Soluble Urokinase Plasminogen Activator Receptor at the Emergency Department: A Position Paper by the Hellenic Sepsis Study Group

被引:0
作者
Dimitrios Velissaris
George Dimopoulos
John Parissis
Zoi Alexiou
Nikolaos Antonakos
Dimitrios Babalis
Styliani Gerakari
Vassileios Kaldis
Pantelis Koutoukas
Malvina Lada
Konstantinos Leventogiannis
Ioannis Pantazopoulos
Antonios Papadopoulos
Eftihia Polyzogopoulou
Charalambos Gogos
Apostolos Armaganidis
Evangelos J. Giamarellos-Bourboulis
机构
[1] University of Patras,Department of Internal Medicine and Department of Emergency Medicine
[2] National and Kapodistrian University of Athens,Second Department of Critical Care Medicine, Medical School
[3] National and Kapodistrian University of Athens,Department of Emergency Medicine, Medical School
[4] Thriasio Elefsis General Hospital,Second Department of Internal Medicine
[5] National and Kapodistrian University of Athens,Fourth Department of Internal Medicine, Medical School
[6] Larissa General Hospital Koutlibaneion-Triantafyllion,Department of Emergency Medicine
[7] Tzaneion Piraeus General Hospital,Department of Emergency Medicine
[8] Sismanogleion Athens General Hospital,Department of Emergency Medicine
[9] Sparti General Hospital,Department of Emergency Medicine
[10] Sismanogleion General Hospital,Second Department of Internal Medicine
[11] University of Thessaly,Department of Emergency Medicine, University General Hospital of Larissa, School of Medicine
来源
Infectious Diseases and Therapy | 2020年 / 9卷
关键词
Emergency department; Mortality; suPAR; Triage;
D O I
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摘要
In light of the accumulating evidence on the negative predictive value of soluble urokinase plasminogen activator receptor (suPAR), a group of experts from the fields of intensive care medicine, emergency medicine, internal medicine and infectious diseases frame a position statement on the role of suPAR in the screening of patients admitted to the emergency department. The statement is framed taking into consideration existing publications and our own research experience. The main content of this statement is that sUPAR is a non-specific marker associated with a high negative predictive value for unfavourable outcomes; levels < 4 ng/ml indicate that it is safe to discharge the patient, whereas levels > 6 ng/ml are an alarming sign of risk for unfavourable outcomes. However, the suPAR levels should always be interpreted in light of the patient's history.
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页码:407 / 416
页数:9
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