The pathogenesis and diagnosis of acute kidney injury in multiple myeloma

被引：0
作者：
Colin A. Hutchison
Vecihi Batuman
Judith Behrens
Frank Bridoux
Christophe Sirac
Angela Dispenzieri
Guillermo A. Herrera
Helen Lachmann
Paul W. Sanders
机构：
[1] Renal Institute of Birmingham,Department of Medicine
[2] University Hospital Birmingham and University of Birmingham,Department of Hematology
[3] Section of Nephrology and Hypertension,Department of Nephrology
[4] Tulane University School of Medicine,Department of Medicine, Division of Hematology
[5] St Helier Hospital,Division of Nephrology, Department of Medicine
[6] Poitiers University Hospital,undefined
[7] CNRS UMR 6101,undefined
[8] Limoges University Hospital,undefined
[9] Mayo Clinic,undefined
[10] Nephrocor,undefined
[11] Bostwick Laboratories,undefined
[12] National Amyloidosis Centre and Centre for Nephrology,undefined
[13] University College London Medical School,undefined
[14] University of Alabama,undefined
来源：
Nature Reviews Nephrology | 2012年 / 8卷
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摘要：
Patients with acute kidney injury (AKI) complicating multiple myeloma often have poor outcomes. In this Review, Hutchison et al. discuss the pathogenic role of monoclonal free light chains in inducing proximal tubular damage and cast nephropathy in patients with multiple myeloma. The authors also provide an update on the diagnostic approaches to patients with AKI complicating multiple myeloma.
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页码：43 / 51
页数：8
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