Management of side effects of mTOR inhibitors in tuberous sclerosis patients

被引：4
作者：
Krzysztof Sadowski
Katarzyna Kotulska
Sergiusz Jóźwiak
机构：
[1] The Children’s Memorial Health Institute,Department of Neurology and Epileptology
[2] Warsaw Medical University,Department of Pediatric Neurology
来源：
Pharmacological Reports | 2016年 / 68卷
关键词：
mTOR inhibitors; Sirolimus; Everolimus; Tuberous sclerosis complex;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
mTOR inhibitors represent a relatively new therapeutic option in the management of patients affected by tuberous sclerosis complex (TSC). Randomized clinical trials support the use of everolimus in the treatment of subependymal giant cell astrocytomas (SEGA) and renal angiomyolipomas (AML) related to TSC. Accumulating data suggest also systemic disease-modifying potential of mTOR inhibitors.
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页码：536 / 542
页数：6
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