Recent advances in pluripotent stem cell-derived cardiac organoids and heart-on-chip applications for studying anti-cancer drug-induced cardiotoxicity

Churko JM(2018)Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity Nat Protoc 15 661-undefined

Ebert AD(2004)5-Fluorouracil induces arterial vasocontractions Ann Oncol 162 298-undefined

Lan F(2021)Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice Free Radic Biol Med 12 127-undefined

Diecke S(2013)Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes Cell Stem Cell 2 13-undefined

Huber B(2018)Cardiotoxicity with vascular endothelial growth factor inhibitor therapy NPJ Precis Oncol 3 265-undefined

Mordwinkin NM(2018)Increased afterload augments sunitinib-induced cardiotoxicity in an engineered cardiac microtissue model JACC Basic Trans Sci 6 e23657-undefined

Burridge PW(2011)Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression PLoS ONE 2 e000247-undefined

Li YF(2017)Cardiotoxicity of immune checkpoint inhibitors ESMO Open 13 332-undefined

Matsa E(2022)Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform Toxicol Sci: Off J Soc Toxicol 20 616-undefined

Wu H(2022)Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling Stem Cell Res Ther 15 2128-undefined

Churko JM(2018)Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity Nat Protoc 15 661-undefined

Ebert AD(2004)5-Fluorouracil induces arterial vasocontractions Ann Oncol 162 298-undefined

Lan F(2021)Xanthine oxidase inhibition attenuates doxorubicin-induced cardiotoxicity in mice Free Radic Biol Med 12 127-undefined

Diecke S(2013)Distinct metabolic flow enables large-scale purification of mouse and human pluripotent stem cell-derived cardiomyocytes Cell Stem Cell 2 13-undefined

Huber B(2018)Cardiotoxicity with vascular endothelial growth factor inhibitor therapy NPJ Precis Oncol 3 265-undefined

Mordwinkin NM(2018)Increased afterload augments sunitinib-induced cardiotoxicity in an engineered cardiac microtissue model JACC Basic Trans Sci 6 e23657-undefined

Burridge PW(2011)Efficient and scalable purification of cardiomyocytes from human embryonic and induced pluripotent stem cells by VCAM1 surface expression PLoS ONE 2 e000247-undefined

Li YF(2017)Cardiotoxicity of immune checkpoint inhibitors ESMO Open 13 332-undefined

Matsa E(2022)Predicting human cardiac QT alterations and pro-arrhythmic effects of compounds with a 3D beating heart-on-chip platform Toxicol Sci: Off J Soc Toxicol 20 616-undefined

Wu H(2022)Characterization of cardiac metabolism in iPSC-derived cardiomyocytes: lessons from maturation and disease modeling Stem Cell Res Ther 15 2128-undefined