Nucleophilic substitution in 1,5-benzodiazepin-2-ones

被引:0
作者
Bozhanov V.I. [1 ]
Ivonin S.P. [1 ]
机构
[1] Dnepropetrovsk State University, UKR
关键词
1,5-benzodiazepin-2-ones; Bromination; phase-transfer catalysis; Nucleophilic substitution; Thiazolo[4,5-b][1,5]benzodiazepine;
D O I
10.1023/A:1017578614850
中图分类号
学科分类号
摘要
The reaction of 3-bromo-4-phenyl-2,3-dihydro-1H -1,5-benzodiazepin-2-one with cyclic amines gives 3-aminoalkyl-4-phenyl-2,3-dihydro-1H-1,5-benzodiazepin-2-one. Thiazolo[4, 5-b][1,5]benzodiazepine was isolated along with the substitution product when thiourea was used.
引用
收藏
页码:1446 / 1448
页数:2
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