The Role of non-NMDA-Receptors in the Process of Associative Learning in the Honeybee Apis mellifera

被引：0
作者：
N. N. Lopatina
I. V. Ryzhova
E. G. Chesnokova
机构：
[1] Russian Academy of Sciences,Pavlov Institute of Physiology
来源：
Journal of Evolutionary Biochemistry and Physiology | 2002年 / 38卷
关键词：
Apis Mellifera; Conditional Reflex; Associative Learn; Pharmacological Profile; Kainate Receptor;
D O I：
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摘要：
Pharmacological parameters of non-NMDA-receptors and their participation in the associative learning in the honeybee Apis mellifera L. have been studied using the method of conditional reflexes and pharmacological analysis. The effect of 1-amino-3-hydroxy-5-methyl, 4-isoxazolprpionate (AMPA), kainate, domoate, antagonist of AMPA-receptors NS-257 HCl and modulator of AMPA-receptors cyclothiazide was studied on retention of the elaborated conditional reflex in short- and long-term memory. It was shown that AMPA-receptors, but not kainate receptors, are involved in the process of formation of short-term memory and are characterized by pharmacological profile similar with that in molluscs. Coactivation of AMPA- and NMDA-receptors is considered as one of possible mechanisms of formation of short-term memory in the honeybee.
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页码：211 / 217
页数：6
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