Intracerebral hemorrhage in two patients with Down’s syndrome and cerebral amyloid angiopathy

被引：0

作者：

John E. Donahue

Jasvir S. Khurana

Lester S. Adelman

机构：

[1] Department of Neurology,

[2] Tufts University School of Medicine and New England Medical Center,undefined

[3] 750 Washington St.,undefined

[4] Boston,undefined

[5] MA 02111,undefined

[6] USA,undefined

[7] Department of Pathology (Division of Neuropathology),undefined

[8] Tufts University School of Medicine and New England Medical Center,undefined

[9] 750 Washington St.,undefined

[10] Boston,undefined

[11] MA 02111,undefined

[12] USA,undefined

[13] Department of Neuropathology,undefined

[14] Rhode Island Hospital,undefined

[15] 593 Eddy St.,undefined

[16] Providence,undefined

[17] RI 02903,undefined

[18] USA Tel.: 1-401-444-8524; Fax: 1-401-444-8514,undefined

来源：

Acta Neuropathologica | 1998年 / 95卷

关键词：

Key words Cerebral amyloid angiopathy; Lobar cerebral hemorrhage; Down’s syndrome; Alzheimer’s disease; Hereditary cerebral hemorrhage;

D O I：

暂无

中图分类号：

学科分类号：

摘要：

Cerebral amyloid angiopathy (CAA) is an important cause of spontaneous intracerebral hemorrhages in the elderly and is often seen in the brains of patients with Alzheimer’s disease, Down’s syndrome (DS), and hereditary cerebral hemorrhage with amyloidosis of the Dutch type. We report two patients with DS and extensive CAA who died of intracerebral hemorrhage; only two other such case reports exist in the literature. We believe the incidence of such cases is higher than is reported and that the likelihood of hemorrhage in the setting of CAA is independent of the patient’s underlying disease.

引用

页码：213 / 216

页数：3