Computer modeling of the solution conformation of cyclic enkephalins

被引：0
|
作者：
Joanna Malicka
Małgorzata Groth
Cezary Czaplewski
Regina Kasprzykowska
Adam Liwo
Leszek Łankiewicz
Wieslaw Wiczk
机构：
[1] University of Gdańsk,Faculty of Chemistry
来源：
Letters in Peptide Science | 1998年 / 5卷
关键词：
computer modeling; conformation; enkephalins; fluorescence; NMR;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
The probable conformations of two cyclic enkephalin analogs, DNS-cyclo[d-Dab-Gly-Trp-Leu] (I) and DNS-cyclo[d-Dab-Gly-Trp-d-Leu] (II) (DNS=dansyl), were determined by combining the results of NOE, vicinal coupling constant and fluorescence energy transfer measurements with theoretical calculations. The common feature of the conformations for both peptides is the presence of a β-turn at residues 2 and 3.
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页码：445 / 447
页数：2
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