Innate immune cell genetic risk factors are linked to COVID-19 severity

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Nature Genetics | 2023年 / 55卷
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Single-cell RNA-sequencing analysis combined with host genetic data for a Japanese population reveals the dysfunction of innate immune cells, particularly non-classical monocytes, in individuals with severe COVID-19, as well as enrichment of host genetic risk factors for severe COVID-19 in monocytes and dendritic cells.
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页码:742 / 743
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