Plasma neurofilament light chain and amyloid-β are associated with the kynurenine pathway metabolites in preclinical Alzheimer’s disease

被引:0
作者
Pratishtha Chatterjee
Henrik Zetterberg
Kathryn Goozee
Chai K. Lim
Kelly R. Jacobs
Nicholas J. Ashton
Abdul Hye
Steve Pedrini
Hamid R. Sohrabi
Tejal Shah
Prita R. Asih
Preeti Dave
Kaikai Shen
Kevin Taddei
David B. Lovejoy
Gilles J. Guillemin
Kaj Blennow
Ralph N. Martins
机构
[1] Macquarie University,Department of Biomedical Sciences
[2] Edith Cowan University,School of Medical Health and Sciences
[3] University of Gothenburg,Department of Psychiatry and Neurochemistry, Institute of Neuroscience and Physiology
[4] Sahlgrenska University Hospital,Clinical Neurochemistry Laboratory
[5] UCL Institute of Neurology,Department of Neurodegenerative Disease
[6] Queen Square,Clinical Research Department
[7] UK Dementia Research Institute at UCL,School of Psychiatry and Clinical Neurosciences
[8] KaRa Institute of Neurological Disease,Institute of Psychiatry, Psychology and Neuroscience, Maurice Wohl Institute Clinical Neuroscience Institute
[9] Sydney,NIHR Biomedical Research Centre for Mental Health and Biomedical Research Unit for Dementia
[10] Anglicare,Wallenberg Centre for Molecular and Translational Medicine
[11] Sydney,School of Medical and Health Sciences
[12] University of Western Australia,undefined
[13] King’s College London,undefined
[14] South London and Maudsley NHS Foundation,undefined
[15] University of Gothenburg,undefined
[16] Australian Alzheimer’s Research Foundation,undefined
[17] Australian eHealth Research Centre,undefined
[18] CSIRO,undefined
[19] The Cooperative Research Centre for Mental Health,undefined
[20] Edith Cowan University,undefined
[21] Ralph & Patricia Sarich Neuroscience Research Institute,undefined
来源
Journal of Neuroinflammation | / 16卷
关键词
Blood markers; Neuroinflammation; Neurodegeneration; Alzheimer’s disease; Neurofilament light chain; Amyloid-beta; Kynurenine pathway; Brain amyloid-beta; Blood amyloid-beta;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [31] Plasma Amyloid-β Forms in Alzheimer's Disease and Non-Alzheimer's Disease Patients
    Le Bastard, Nathalie
    Leurs, Judith
    Blomme, Walter
    De Deyn, Peter Paul
    Engelborghs, Sebastiaan
    JOURNAL OF ALZHEIMERS DISEASE, 2010, 21 (01) : 291 - 301
  • [32] Plasma neurofilament light chain as a biomarker of Alzheimer's disease in Subjective Cognitive Decline and Mild Cognitive Impairment
    Giacomucci, Giulia
    Mazzeo, Salvatore
    Bagnoli, Silvia
    Ingannato, Assunta
    Leccese, Deborah
    Berti, Valentina
    Padiglioni, Sonia
    Galdo, Giulia
    Ferrari, Camilla
    Sorbi, Sandro
    Bessi, Valentina
    Nacmias, Benedetta
    JOURNAL OF NEUROLOGY, 2022, 269 (08) : 4270 - 4280
  • [33] Therapeutic Potential of Direct Clearance of the Amyloid-β in Alzheimer's Disease
    Kim, Dong Eun
    Priefer, Ronny
    BRAIN SCIENCES, 2020, 10 (02)
  • [34] Integration of amyloid-β oligomerization tendency as a plasma biomarker in Alzheimer's disease diagnosis
    Pyun, Jung-Min
    Youn, Young Chul
    Park, Young Ho
    Kim, SangYun
    FRONTIERS IN NEUROLOGY, 2023, 13
  • [35] Synaptic Retrogenesis and Amyloid-β in Alzheimer's Disease
    Wasling, Pontus
    Daborg, Jonny
    Riebe, Ilse
    Andersson, My
    Portelius, Erik
    Blennow, Kaj
    Hanse, Eric
    Zetterberg, Henrik
    JOURNAL OF ALZHEIMERS DISEASE, 2009, 16 (01) : 1 - 14
  • [36] Multiplex immunoassay measurement of amyloid-β42 to amyloid-β40 ratio in plasma discriminates between dementia due to Alzheimer's disease and dementia not due to Alzheimer's disease
    Vogelgsang, Jonathan
    Shahpasand-Kroner, Hedieh
    Vogelgsang, Rebekka
    Streit, Frank
    Vukovich, Ruth
    Wiltfang, Jens
    EXPERIMENTAL BRAIN RESEARCH, 2018, 236 (05) : 1241 - 1250
  • [37] Plasma Neurofilament Light Combined with Risk Genes for the Diagnosis of Alzheimer's Disease
    Zhang, S. Z.
    Mei, F.
    Gao, M. L.
    Zhang, Li
    Ma, Li
    Wu, Haiyan
    Liu, L. X.
    Cao, M.
    He, X. L.
    INDIAN JOURNAL OF PHARMACEUTICAL SCIENCES, 2021, 83 : 253 - 259
  • [38] Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease
    Schultz, Stephanie A.
    Strain, Jeremy F.
    Adedokun, Adedamola
    Wang, Qing
    Preische, Oliver
    Kuhle, Jens
    Flores, Shaney
    Keefe, Sarah
    Dincer, Aylin
    Ances, Beau M.
    Berman, Sarah B.
    Brickman, Adam M.
    Cash, David M.
    Chhatwal, Jasmeer
    Cruchaga, Carlos
    Ewers, Michael
    Fox, Nick N.
    Ghetti, Bernardino
    Goate, Alison
    Graff-Radford, Neill R.
    Hassenstab, Jason J.
    Hornbeck, Russ
    Jack, Clifford, Jr.
    Johnson, Keith
    Joseph-Mathurin, Nelly
    Karch, Celeste M.
    Koeppe, Robert A.
    Lee, Athene K. W.
    Levin, Johannes
    Masters, Colin
    McDade, Eric
    Perrin, Richard J.
    Rowe, Christopher C.
    Salloway, Stephen
    Saykin, Andrew J.
    Sperling, Reisa
    Su, Yi
    Villemagne, Victor L.
    Voeglein, Jonathan
    Weiner, Michael
    Xiong, Chengjie
    Fagan, Anne M.
    Morris, John C.
    Bateman, Randall J.
    Benzinger, Tammie L. S.
    Jucker, Mathias
    Gordon, Brian A.
    NEUROBIOLOGY OF DISEASE, 2020, 142
  • [39] Neurofilament Light Chain as a Potential Biomarker in Plasma for Alzheimer's Disease and Mild Cognitive Impairment: A Systematic Review and a Meta-Analysis
    Fan, Zhenyi
    Liu, Xiaoxia
    Liu, Jie
    Chen, Caijing
    Zhou, Min
    JOURNAL OF INTEGRATIVE NEUROSCIENCE, 2023, 22 (04)
  • [40] Plasma amyloid-/3 precursor protein 669-711 /amyloid-β-42 ratio is associated with cognition in Alzheimer's disease
    Noguchi-Shinohara, Moeko
    Sakashita, Yasuhiro
    Nakano, Hiroto
    Muramatsu, Daiki
    Hikishima, Sadao
    Komatsu, Junji
    Murakami, Hidetomo
    Mori, Yukiko
    Ono, Kenjiro
    JPAD-JOURNAL OF PREVENTION OF ALZHEIMERS DISEASE, 2025, 12 (01): : 100003