Preoperative idoxuridine and radiation for large soft tissue sarcomas: Clinical results with five-year follow-up

被引：0
作者：
Vernon K. Sondak
John M. Robertson
Jeffrey J. Sussman
Patricia A. Saran
Alfred E. Chang
Theodore S. Lawrence
机构：
[1] University of Michigan Medical Center,From the Department of Surgery
[2] University of Michigan Medical Center,the Department of Radiation Oncology
[3] William Beaumont Hospital,the Department of Radiation Oncology
[4] University of Cincinnati Medical Center,the Department of Surgery
[5] University of Michigan Medical Center,Div. of Surgical Oncology
[6] 3306 Comprehensive Cancer/Geriatrics Center,undefined
来源：
Annals of Surgical Oncology | 1998年 / 5卷
关键词：
Idoxuridine; Radiation sensitizers; Soft tissue sarcomas; Radiotherapy; Surgery;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Background: Local control remains an important issue in the management of large soft tissue sarcomas. Radiation is the main adjuvant to surgery for local therapy of sarcomas, but it requires relatively high doses, hitherto considered prohibitive in areas such as the retroperitoneum. We developed a preoperative treatment approach to large soft tissue sarcomas that would deliver a high total dose of radiation administered in conjunction with the halogenated pyrimidine radiosensitizer idoxuridine (IdUrd).
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页码：106 / 112
页数：6
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