Pharmacological characterisation of ligand- and voltage-gated ion channels expressed in human iPSC-derived forebrain neurons

被引:0
|
作者
Jeffrey L. Dage
Ellen M. Colvin
Antoine Fouillet
Emily Langron
William C. Roell
Jingling Li
Sachin X. Mathur
Adrian J. Mogg
Matthew G. Schmitt
Christian C. Felder
Kalpana M. Merchant
John Isaac
Lisa M. Broad
Emanuele Sher
Daniel Ursu
机构
[1] Eli Lilly and Company,Lilly Research Laboratories
[2] Eli Lilly and Company,Lilly Research Center
来源
Psychopharmacology | 2014年 / 231卷
关键词
IPSC; Stem cells; Ion channels; Glutamate receptors; GABA; receptors;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:1105 / 1124
页数:19
相关论文
共 50 条
  • [21] Developmental regulation of voltage-gated ion channels in trigeminal neurons
    Saha, S
    Turman, JE
    ANNALS OF NEUROLOGY, 2004, 56 : S39 - S39
  • [22] Voltage-gated ion channels in dendrites of hippocampal pyramidal neurons
    Xixi Chen
    Daniel Johnston
    Pflügers Archiv, 2006, 453 : 397 - 401
  • [23] Ligand- and voltage-gated Ca2+ channels differentially regulate the mode of vesicular neuropeptide release in mammalian sensory neurons
    Wang, Yeshi
    Wu, Qihui
    Hu, Meiqin
    Liu, Bin
    Chai, Zuying
    Huang, Rong
    Wang, Yuan
    Xu, Huadong
    Zhou, Li
    Zheng, Lianghong
    Wang, Changhe
    Zhou, Zhuan
    SCIENCE SIGNALING, 2017, 10 (484)
  • [24] Phosphorylation of voltage-gated ion channels in rat olfactory receptor neurons
    Wetzel, CH
    Spehr, M
    Hatt, H
    EUROPEAN JOURNAL OF NEUROSCIENCE, 2001, 14 (07) : 1056 - 1064
  • [25] Role of voltage-gated ion channels in essential operations of central neurons
    Roeper, J.
    ACTA PHYSIOLOGICA, 2017, 219 : 11 - 11
  • [26] An Electrophysiological and Pharmacological Study of the Properties of Human iPSC-Derived Neurons for Drug Discovery
    Halliwell, Robert F.
    Salmanzadeh, Hamed
    Coyne, Leanne
    Cao, William S.
    CELLS, 2021, 10 (08)
  • [27] Ligand- and Structure-Based Virtual Screening for Clathrodin-Derived Human Voltage-Gated Sodium Channel Modulators
    Tomasic, Tihomir
    Hartzoulakis, Basil
    Zidar, Nace
    Chan, Fiona
    Kirby, Robert W.
    Madge, David J.
    Peigneur, Steve
    Tytgat, Jan
    Kikelj, Danijel
    JOURNAL OF CHEMICAL INFORMATION AND MODELING, 2013, 53 (12) : 3223 - 3232
  • [28] HUMAN FETAL CENTRAL NEURONS IN CULTURE - VOLTAGE-GATED AND LIGAND-GATED CURRENTS
    SAH, DWY
    JOURNAL OF NEUROPHYSIOLOGY, 1995, 74 (05) : 1889 - 1899
  • [29] Selected Ionotropic Receptors and Voltage-Gated Ion Channels: More Functional Competence for Human Induced Pluripotent Stem Cell (iPSC)-Derived Nociceptors
    Schoepf, Clemens L.
    Zeidler, Maximilian
    Spiecker, Lisa
    Kern, Georg
    Lechner, Judith
    Kummer, Kai K.
    Kress, Michaela
    BRAIN SCIENCES, 2020, 10 (06)
  • [30] Drug Development in Channelopathies: Allosteric Modulation of Ligand-Gated and Voltage-Gated Ion Channels
    Zhang, Yanyun
    Wang, Ke
    Yu, Zhiyi
    JOURNAL OF MEDICINAL CHEMISTRY, 2020, 63 (24) : 15258 - 15278