Respiratory complex I is essential to induce a Warburg profile in mitochondria-defective tumor cells

被引:0
作者
Claudia Calabrese
Luisa Iommarini
Ivana Kurelac
Maria Antonietta Calvaruso
Mariantonietta Capristo
Pier-Luigi Lollini
Patrizia Nanni
Christian Bergamini
Giordano Nicoletti
Carla De Giovanni
Anna Ghelli
Valentina Giorgio
Mariano Francesco Caratozzolo
Flaviana Marzano
Caterina Manzari
Christine M Betts
Valerio Carelli
Claudio Ceccarelli
Marcella Attimonelli
Giovanni Romeo
Romana Fato
Michela Rugolo
Apollonia Tullo
Giuseppe Gasparre
Anna Maria Porcelli
机构
[1] Università di Bologna,Dip. Scienze Mediche e Chirurgiche (DIMEC), U.O. Genetica Medica, Pol. Universitario S. Orsola
[2] Università di Bologna,Malpighi
[3] Università di Bologna,Dip. Farmacia e Biotecnologie (FABIT)
[4] Istituti Ortopedici Rizzoli,Dip. Medicina Specialistica, Diagnostica e Sperimentale
[5] Università di Padova,Laboratorio di Oncologia Sperimentale
[6] Consiglio Nazionale delle Ricerche (CNR),Dip. Scienze Biomediche
[7] Università di Bari,Istituto di Tecnologie Biomediche
[8] IRCCS Istituto delle Scienze Neurologiche, ITB
[9] Università di Bologna,Dip. Bioscienze, Biotecnologie e Scienze Farmacologiche
[10] Università di Bologna,Dip. Sc. Radiologiche ed Istopatologiche, Pol. Universitario S.Orsola
关键词
Complex I; mtDNA mutation; HIF-1α; Mitochondria; Cancer; Warburg effect; Allotopic expression;
D O I
10.1186/2049-3002-1-11
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