机构:Smita Gopinath,Yosuke Kumamoto and Akiko Iwasaki are in the Department of Immunobiology
Smita Gopinath
Yosuke Kumamoto
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机构:Smita Gopinath,Yosuke Kumamoto and Akiko Iwasaki are in the Department of Immunobiology
Yosuke Kumamoto
Akiko Iwasaki
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机构:Smita Gopinath,Yosuke Kumamoto and Akiko Iwasaki are in the Department of Immunobiology
Akiko Iwasaki
机构:
[1] Smita Gopinath,Yosuke Kumamoto and Akiko Iwasaki are in the Department of Immunobiology
[2] Howard Hughes Medical Institute,undefined
[3] Yale University School of Medicine,undefined
[4] New Haven,undefined
[5] Connecticut,undefined
[6] USA.,undefined
来源:
Nature Immunology
|
2016年
/
17卷
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摘要:
Viral infection of the mucosa induces a strong host innate immune response involving type I interferons and interferon-stimulated genes. New findings show that mechanical or pathogen-induced disruption of the mucus itself can also trigger 'hyper-early' innate responses independent of type I interferons and major sensing pathways of the innate immune system.
Zhe Qiao aChengxue Dang bBin Zhou aShaomin Li aWei Zhang aJiantao Jiang aJin Zhang aRanran Kong aYuefeng Ma a a Department of Thoracic Surgerythe Second Affiliated HospitalXian Jiaotong UniversityXianShaanxi China
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Zhe Qiao aChengxue Dang bBin Zhou aShaomin Li aWei Zhang aJiantao Jiang aJin Zhang aRanran Kong aYuefeng Ma a a Department of Thoracic Surgerythe Second Affiliated HospitalXian Jiaotong UniversityXianShaanxi China
b Department of Surgical Oncologythe First Affiliated HospitalXian Jiaotong UniversityXianShaanxi China
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b Department of Surgical Oncologythe First Affiliated HospitalXian Jiaotong UniversityXianShaanxi China