O-linked sugars sound the alarm

被引：0
|
作者：
Smita Gopinath
Yosuke Kumamoto
Akiko Iwasaki
机构：
[1] Smita Gopinath,Yosuke Kumamoto and Akiko Iwasaki are in the Department of Immunobiology
[2] Howard Hughes Medical Institute,undefined
[3] Yale University School of Medicine,undefined
[4] New Haven,undefined
[5] Connecticut,undefined
[6] USA.,undefined
来源：
Nature Immunology | 2016年 / 17卷
关键词：
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Viral infection of the mucosa induces a strong host innate immune response involving type I interferons and interferon-stimulated genes. New findings show that mechanical or pathogen-induced disruption of the mucus itself can also trigger 'hyper-early' innate responses independent of type I interferons and major sensing pathways of the innate immune system.
引用
收藏
页码：119 / 120
页数：1
相关论文
共 50 条
  • [31] Decoding of O-Linked Glycosylation by Mass Spectrometry
    Mulagapati, SriHariRaju t
    Koppolu, Veerendra
    Raju, T. Shantha
    BIOCHEMISTRY, 2017, 56 (09) : 1218 - 1226
  • [32] Profiling the morphological distribution of O-linked oligosaccharides
    Zhang, JH
    Xie, YM
    Hedrick, JL
    Lebrilla, CB
    ANALYTICAL BIOCHEMISTRY, 2004, 334 (01) : 20 - 35
  • [33] A strategy to discover inhibitors of O-linked glycosylation
    Gross, Benjamin J.
    Swoboda, Jonathan G.
    Walker, Suzanne
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2008, 130 (02) : 440 - +
  • [34] BOLD -: A biological O-linked glycan database
    Cooper, CA
    Wilkins, MR
    Williams, KL
    Packer, NH
    ELECTROPHORESIS, 1999, 20 (18) : 3589 - 3598
  • [35] Regulation of notch signaling by O-linked fucose
    Okajima, T
    Irvine, KD
    CELL, 2002, 111 (06) : 893 - 904
  • [36] STUDIES OF O-LINKED FUCOSE CONTAINING GLYCOPROTEINS
    MORTON, PA
    KLINGER, MM
    STEINER, S
    FEDERATION PROCEEDINGS, 1983, 42 (07) : 2098 - 2098
  • [37] Mass spectrometry in the analysis of N-linked and O-linked glycans
    North, Simon J.
    Hitchen, Paul G.
    Haslam, Stuart M.
    Dell, Anne
    CURRENT OPINION IN STRUCTURAL BIOLOGY, 2009, 19 (05) : 498 - 506
  • [38] Metabolism of Vertebrate Amino Sugars with N-Glycolyl Groups INTRACELLULAR β-O-LINKED N-GLYCOLYLGLUCOSAMINE (GlcNGc), UDP-GlcNGc, AND THE BIOCHEMICAL AND STRUCTURAL RATIONALE FOR THE SUBSTRATE TOLERANCE OF β-O-LINKED β-N-ACETYLGLUCOSAMINIDASE
    Macauley, Matthew S.
    Chan, Jefferson
    Zandberg, Wesley F.
    He, Yuan
    Whitworth, Garrett E.
    Stubbs, Keith A.
    Yuzwa, Scott A.
    Bennet, Andrew J.
    Varki, Ajit
    Davies, Gideon J.
    Vocadlo, David J.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2012, 287 (34) : 28882 - 28897
  • [39] EFFECT OF TUNICAMYCIN AND MONENSIN ON THE TRANSPORT TO THE CELL-SURFACE AND SECRETION OF A VIRAL MEMBRANE GLYCOPROTEIN CONTAINING BOTH N-LINKED AND O-LINKED SUGARS
    GHOSHCHOUDHURY, N
    BUTCHER, M
    REID, E
    GHOSH, HP
    BIOCHEMISTRY AND CELL BIOLOGY-BIOCHIMIE ET BIOLOGIE CELLULAIRE, 1994, 72 (1-2): : 20 - 25
  • [40] ENZYMATIC-SYNTHESIS OF N-LINKED AND O-LINKED GLYCOPEPTIDES
    WONG, CH
    SCHUSTER, M
    WANG, P
    SEARS, P
    JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1993, 115 (14) : 5893 - 5901
12345