Randomized controlled trial of vaginal misoprostol versus vaginal misoprostol and isosorbide dinitrate for termination of pregnancy at 13-29 weeks.

被引：12
作者：
Hidar S. [1 ]
Bouddebous M. [1 ]
Chaïeb A. [1 ]
Jerbi M. [1 ]
Bibi M. [1 ]
Khaïri H. [1 ]
机构：
[1] Department of Obstetrics and Gynaecology, Farhat Hached University Teaching Hospital, Sousse
来源：
Archives of Gynecology and Obstetrics | 2005年 / 273卷 / 3期
关键词：
Misoprostol; Mifepristone; Isosorbide Dinitrate; Nitric Oxide Donor; Isosorbide Mononitrate;
D O I：
10.1007/s00404-005-0053-7
中图分类号：
学科分类号：
摘要：
When compared to the use of 12 hourly 200 microg vaginal misoprostol on its own, the addition of a single dose of 5 mg did not significantly increase the abortion or delivery rate in pregnancy termination at 13-29 weeks gestation. All patients were given intravenous syntocinon at 30 mU/min from the first dose of misoprostol onwards.
引用
收藏
页码：157 / 160
页数：3
相关论文
共 118 条
  • [1] Hamoda H(2004)A randomized controlled comparison of sublingual and vaginal administration of misoprostol for cervical priming before first-trimester surgical abortion Am J Obstet Gynecol 190 55-59
  • [2] Ashok PW(2004)Randomized controlled trial of misoprostol for second-trimester pregnancy termination associated with fetal malformation Am J Obstet Gynecol 190 755-762
  • [3] Flett GM(2004)Oral, rectal, and vaginal pharmacokinetics of misoprostol Obstet Gynecol 103 866-870
  • [4] Templeton A(2001)Use of misoprostol for the termination of second trimester pregnancies Arch Gynecol Obstet 265 204-206
  • [5] Akoury HA(2002)Misoprostol use in obstetrics and gynecology in Brazil, Jamaica, and the United States Int J Gynaecol Obstet 76 65-74
  • [6] Hannah ME(1995)Reducing the induction to abortion interval in termination of second trimester pregnancies: a comparison of mifepristone with laminaria tent Br J Obstet Gynaecol 102 648-651
  • [7] Chitayat D(1995)Induction of abortion in the second trimester by a combination of misoprostol and mifepristone: a randomized comparison between two misoprostol regimens Hum Reprod 10 475-478
  • [8] Thomas M(2001)Oxytocin and misoprostol administered intravaginally for termination of pregnancy at 13–29 weeks of amenorrhea. A prospective randomized trial J Gynecol Obstet Biol Reprod (Paris) 30 439-443
  • [9] Winsor E(1998)Randomised trial of nitric oxide donor versus prostaglandin for cervical ripening before first-trimester termination of pregnancy Lancet 352 1093-1096
  • [10] Ferris LE(2001)A comparison of isosorbide monoitrate, misoprostol and combination therapy for first trimester pre-operative cervical ripening: a randomised controlled trial BJOG 108 276-280
12345678910