Emerging role of epithelial-mesenchymal transition in hepatic cancer

被引：0
|
作者：
Go J. Yoshida
机构：
[1] Medical Research Institute,Department of Pathological Cell Biology
[2] Tokyo Medical and Dental University,undefined
[3] Japan Society for the Promotion of Science,undefined
来源：
Journal of Experimental & Clinical Cancer Research | / 35卷
关键词：
Cancer stem-like cells; Cirrhosis; Epithelial-mesenchymal transition; Hepatic cancer; Matrix metalloproteinases; Wnt/beta-catenin signal;
D O I：
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学科分类号：
摘要：
Accumulating evidence suggests that the phenomenon of epithelial-mesenchymal-transition (EMT) plays a fundamental role in the tumor development. Several research articles have been published from Journal of Experimental and Clinical Cancer Research (JECCR) which have investigated into the molecular machineries underlying the importance of EMT for hepatic cancer. Given those recent publications by JECCR, this commentary focuses on the pathological significance of EMT for liver tumor.
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