Femoral neck bone mineral density and 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 years and older

被引：9

作者：

Borissova A.-M. ^{[1
]}

Rashkov R. ^{[2
]}

Boyanov M. ^{[3
]}

Shinkov A. ^{[1
]}

Popivanov P. ^{[4
]}

Temelkova N. ^{[4
]}

Vlahov J. ^{[1
]}

Gavrailova M. ^{[5
]}

机构：

[1] Thyroid and Bone Metabolic Clinic, University Hospital for Endocrinology and Gerontology, Medical University Sofia, Sofia

[2] Rheumatology Clinic, University Hospital St. Ivan Rilski, Medical University Sofia, Sofia

[3] Endocrinology Clinic, University Hospital Alexandrovska, Medical University Sofia, Sofia 1431

[4] Bone Metabolic Unit, University Hospital Alexandrovska, Medical University Sofia, Sofia

[5] Public Health Department, Ministry of Health, Sofia

来源：

Archives of Osteoporosis | 2011年 / 6卷 / 1-2期

关键词：

Epidemiology; FRAX®; Osteoporosis; Risk assessment;

D O I：

10.1007/s11657-011-0064-x

中图分类号：

学科分类号：

摘要：

Summary This study explored the epidemiology of osteoporosis in Bulgarian women (>50 years). Of the women included in the study, 16.8% had osteoporosis and 46.5% had osteopenia at the femoral neck. The mean 10-year absolute fracture risk was 13.4±9.2% (major fractures) and 2.8±5.2% (hip fractures). This study is the largest Bulgarian epidemiological osteoporosis trial. Purpose The aim of this study was to determine the prevalence of the major risk factors for osteoporosis and the 10-year absolute fracture risk in a national representative sample of Bulgarian women aged 50 and older. Methods This work is a part of the Bulgarian Osteoporosis Epidemiology Study. The National Statistical Institute selected a national representative epidemiological sample. A questionnaire was used allowing fracture risk calculation according to FRAX. Ten osteoporosis centers throughout the country participated. Bone mineral density (BMD) was measured at the femoral neck by dual X-ray absorptiometry. The statistical analysis was performed on a SPSS 13.0 for windows platform. Results A total of 1,331 women were included (mean age 63.8±8.3 years), divided into decades. Of them, 16.8% had osteoporosis and 46.5% had low femoral neck BMD. Their mean 10-year absolute fracture risk for major fractures was 13.4±9.2%, and for hip fractures 2.8±5.2%, respectively. The prevalence of some major risk factors for osteoporosis was as follows: height loss>3 cm-33.1% of all women; family history of hip fractures-4.1%; previous hip fractures-1.9%; previous vertebral fractures-2.3%; all fractures-23.3%; smoking-11.9%. Conclusions This study is the largest epidemiological osteoporosis trial in Bulgaria to date and allows assumptions about the prevalence of osteoporosis and fractures among women aged 50 and older in our country. © International Osteoporosis Foundation and National Osteoporosis Foundation 2011.

引用

页码：189 / 195

页数：6

共 29 条

[1]

Boyanov M., Popivanov P., Prevalence of low forearm bone density in a Bulgarian female referral population, Osteoporosis International, 13, 4, pp. 288-295, (2002)

[2]

Boyanov M., Prevalence of low central bone mineral density in a Bulgarian female referral population: A pilot study, Rheumatol Int, 26, pp. 523-529, (2006)

[3]

Borissova A.-M., Kovatcheva R., Shinkov A., Et al., Nutrition, physical activity and harmful habits in middle-aged Bulgarian women, Endokrinologia, 5, pp. 46-54, (2000)

[4]

Slavchev A., Boyanov M., Impact of precision on long-term patient monitoring during osteoporosis treatment. In, IFMBE Proceedings, 25, 7, pp. 352-355, (2009)

[5]

Technical standardization for dual-energy X-ray absorptiometry, J Clin Densitom, 7, pp. 27-36, (2004)

[6]

Lu Y., Fuerst T., Hui S., Genant H.K., Standardization of bone mineral density at femoral neck, trochanter and ward's triangle, Osteoporosis International, 12, 6, pp. 438-444, (2001)

[7]

Kanis J.A., Johnell O., Oden A., Borgstrom F., Johansson H., De Laet C., Jonsson B., Intervention thresholds for osteoporosis in men and women: A study based on data from Sweden, Osteoporosis International, 16, 1, pp. 6-14, (2005)

[8]

Haussler B., Gothe H., Gol D., Glaeske G., Pientka L., Felsenberg D., Epidemiology, treatment and costs of osteoporosis in Germany - The BoneEVA Study, Osteoporosis International, 18, 1, pp. 77-84, (2007)

[9]

Looker A.C., Melton III L.J., Harris T.B., Borrud L.G., Shepherd J.A., Prevalence and trends in low femur bone density among older US adults: NHANES 2009-2996 compared with NHANES III, J Bone Miner Res, 25, pp. 64-71, (2010)

[10]

Tenenhouse A., Joseph L., Kreiger N., Poliquin S., Murray T.M., Blondeau L., Berger C., Hanley D.A., Prior J.C., Estimation of the prevalence of low bone density in Canadian women and men using a population-specific DXA reference standard: The Canadian Multicentre Osteoporosis Study (CaMos), Osteoporosis International, 11, 10, pp. 897-904, (2000)

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