Impact of non-pharmacological interventions on prevention and treatment of delirium in critically ill patients: Protocol for a systematic review of quantitative and qualitative research

被引：23
作者：
Bannon L. [1 ]
McGaughey J. [2 ]
Clarke M. [3 ]
McAuley D.F. [1 ]
Blackwood B. [1 ]
机构：
[1] Queen's University Belfast, Centre for Infection and Immunity, School of Medicine, Dentistry and Biomedical Sciences, 97 Lisburn Road, Belfast, Northern Ireland
[2] School of Nursing and Midwifery, Queen's University Belfast, 97 Lisburn Road, Belfast, Northern Ireland
[3] Queen's University Belfast, Centre for Public Health, School of Medicine, Dentistry and Biomedical Sciences, Belfast, Northern Ireland
来源：
Systematic Reviews | / 5卷 / 1期
基金：
英国医学研究理事会;
关键词：
Critical illness; Delirium; ICU syndrome; Intensive care unit; Non-pharmacological interventions;
D O I：
10.1186/s13643-016-0254-0
中图分类号：
学科分类号：
摘要：
Background: Critically ill patients have an increased risk of developing delirium during their intensive care stay. To date, pharmacological interventions have not been shown to be effective for delirium management but non-pharmacological interventions have shown some promise. The aim of this systematic review is to identify effective non-pharmacological interventions for reducing the incidence or the duration of delirium in critically ill patients. Methods: We will search MEDLINE, EMBASE, CINAHL, Web of Science, AMED, psycINFO and the Cochrane Library. We will include studies of critically ill adults and children. We will include randomised trials and controlled trials which measure the effectiveness of one or more non-pharmacological interventions in reducing incidence or duration of delirium in critically ill patients. We will also include qualitative studies that provide an insight into patients and their families' experiences of delirium and non-pharmacological interventions. Two independent reviewers will assess studies for eligibility, extract data and appraise quality. We will conduct meta-analyses if possible or present results narratively. Qualitative studies will also be reviewed by two independent reviewers, and a specially designed quality assessment tool incorporating the CASP framework and the POPAY framework will be used to assess quality. Discussion: Although non-pharmacological interventions have been studied in populations outside of intensive care units and multicomponent interventions have successfully reduced incidence and duration of delirium, no systematic review of non-pharmacological interventions specifically targeting delirium in critically ill patients have been undertaken to date. This systematic review will provide evidence for the development of a multicomponent intervention for delirium management of critically ill patients that can be tested in a subsequent multicentre randomised trial. Systematic review registration: PROSPERO CRD42015016625 © 2016 Bannon et al.
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