Involvement of a proline-rich peptide in the regulation of the hemostasis system

被引:0
作者
R. M. Srapionyan
Z. Kh. Paronyan
F. M. Saakyan
A. A. Galoyan
机构
[1] National Academy of Sciences of the Republic of Armenia,Bunyatyan Institute of Biochemistry
来源
Neurochemical Journal | 2014年 / 8卷
关键词
hemostasis; blood coagulation; proline-rich peptide; fibrinogen; anticoagulation;
D O I
暂无
中图分类号
学科分类号
摘要
We studied the effects of a hypothalamic proline-rich peptide on some factors of the hemostasis system. We found dose-dependent acceleration of blood coagulation in the presence of the peptide, which was associated with the activation of anticoagulation factors.
引用
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页码:44 / 46
页数:2
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  • [31] C-terminal sequencing by mass spectrometry:: Application to gelatine-derived proline-rich peptides
    Ocaña, MF
    Jarvis, J
    Parker, R
    Bramley, PM
    Halket, JM
    Patel, RKP
    Neubert, H
    [J]. PROTEOMICS, 2005, 5 (05) : 1209 - 1216
  • [32] all-D proline-rich cell-penetrating peptides:: a preliminary in vivo internalization study
    Pujals, S.
    Sabido, E.
    Tarrago, T.
    Giralt, E.
    [J]. BIOCHEMICAL SOCIETY TRANSACTIONS, 2007, 35 : 794 - 796
  • [33] Analysis of the thermodynamics of binding of an SH3 domain to proline-rich peptides using a chimeric fusion protein
    Candel, Adela M.
    van Nuland, Nico A. J.
    Martin-Sierra, Francisco M.
    Martinez, Jose C.
    Conejero-Lara, Francisco
    [J]. JOURNAL OF MOLECULAR BIOLOGY, 2008, 377 (01) : 117 - 135
  • [34] Proline-Rich Peptides with Improved Antimicrobial Activity against E. coli, K. Pneumoniae, and A. Baumannii
    Mardirossian, Mario
    Sola, Riccardo
    Beckert, Bertrand
    Collis, Dominic W. P.
    Di Stasi, Adriana
    Armas, Federica
    Hilpert, Kai
    Wilson, Daniel N.
    Scocchi, Marco
    [J]. CHEMMEDCHEM, 2019, 14 (24) : 2025 - 2033
  • [35] Evaluation of the Efficacy of Proline Rich VPPPVPPRRR Peptide (VPP) in MCF-7 Cells
    Cevik, Ziysan Buse Yarali
    Sonmez, Berk Bugra
    Karaman, Ozan
    [J]. INTERNATIONAL JOURNAL OF PEPTIDE RESEARCH AND THERAPEUTICS, 2025, 31 (03)
  • [36] The proline-rich tyrosine kinase Pyk2 modulates integrin-mediated neutrophil adhesion and reactive oxygen species generation
    Canino, Jessica
    Guidetti, Gianni Francesco
    Galgano, Luca
    Vismara, Mauro
    Minetti, Giampaolo
    Torti, Mauro
    Canobbio, Ilaria
    [J]. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH, 2020, 1867 (10):
  • [37] SH3 domain of Bruton's tyrosine kinase can bind to proline-rich peptides of TH domain of the kinase and p120(cbl)
    Patel, HV
    Tzeng, SR
    Liao, CY
    Chen, SH
    Cheng, JW
    [J]. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS, 1997, 29 (04) : 545 - 552
  • [38] Small Structural Differences in Proline-Rich Decapeptides Have Specific Effects on Oxidative Stress-Induced Neurotoxicity and L-Arginine Generation by Arginosuccinate Synthase
    Alberto-Silva, Carlos
    da Silva, Brenda Rufino
    da Silva, Julio Cezar Araujo
    Silva, Felipe Assumpcao da Cunha e
    Kodama, Roberto Tadashi
    da Silva, Wilmar Dias
    Costa, Maricilia Silva
    Portaro, Fernanda Calheta Vieira
    [J]. PHARMACEUTICALS, 2024, 17 (07)
  • [39] Effect of a New Synthetic Peptide Preparation AСTH15-18PGP on the Hemostasis System in Rats
    T. A. Shubina
    T. Yu. Obergan
    L. A. Lyapina
    M. E. Grigorieva
    N. F. Myasoedov
    L. A. Andreeva
    [J]. Bulletin of Experimental Biology and Medicine, 2019, 168 : 250 - 253
  • [40] Effect of a New Synthetic Peptide Preparation A.TH15-18PGP on the Hemostasis System in Rats
    Shubina, T. A.
    Obergan, T. Yu.
    Lyapina, L. A.
    Grigorieva, M. E.
    Myasoedov, N. F.
    Andreeva, L. A.
    [J]. BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE, 2019, 168 (02) : 250 - 253