Evaluation of paclitaxel-loaded polymeric nanoparticles in 3D tumor model: impact of tumor stroma on penetration and efficacy

被引：0
|
作者：
Dwi L. Priwitaningrum
Kunal Pednekar
Alexandros V. Gabriël
Aida A. Varela-Moreira
Severine Le Gac
Ivo Vellekoop
Gert Storm
Wim E. Hennink
Jai Prakash
机构：
[1] University of Twente,Engineered Therapeutics, Department of Advanced Organ Bioengineering and Therapeutics, TechMed Centre, Faculty of Science and Technology
[2] Universitas Sumatera Utara,Department of Pharmaceutics, Faculty of Pharmacy
[3] Utrecht University,Department of Pharmaceutics, Utrecht Institute for Pharmaceutical Sciences, Faculty of Science
[4] University of Twente,Applied Microfluidics for BioEngineering Research, Faculty of Electrical Engineering, Mathematics and Computer Science, MESA+ Institute for Nanotechnology, TechMed Centre
[5] University of Twente,Biomedical Photonic Imaging, Faculty of Science and Technology
来源：
Drug Delivery and Translational Research | 2023年 / 13卷
关键词：
Nanomedicine; Polymeric nanoparticles; Tumor stroma; Tumor penetration; 3D spheroids; Therapeutic efficacy;
D O I：
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中图分类号：
学科分类号：
摘要：
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页码：1470 / 1483
页数：13
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