Systemic and central nervous system metabolic alterations in Alzheimer’s disease

被引：0
作者：
Vera van der Velpen
Tony Teav
Héctor Gallart-Ayala
Florence Mehl
Ioana Konz
Christopher Clark
Aikaterini Oikonomidi
Gwendoline Peyratout
Hugues Henry
Mauro Delorenzi
Julijana Ivanisevic
Julius Popp
机构：
[1] University of Lausanne,Metabolomics Unit, Faculty of Biology and Medicine
[2] Lausanne University Hospital,Old Age Psychiatry, Department of Psychiatry
[3] Lausanne University Hospital,Clinical Chemistry Laboratory, Department of Biomedicine
[4] University of Lausanne,Translational Bioinformatics and Statistics, Department of Oncology, Swiss Cancer Center Leman (SCCL)
[5] SIB Swiss Institute of Bioinformatics,Bioinformatics Core Facility
[6] Department of Psychiatry,undefined
[7] University of Geneva,undefined
来源：
Alzheimer's Research & Therapy | / 11卷
关键词：
Alzheimer’s disease; Metabolomics; Energy metabolism; Tryptophan pathway; CSF AD biomarkers;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 304 条
[1]  
Herholz K(2010)Cerebral glucose metabolism in preclinical and prodromal Alzheimer’s disease Expert Rev Neurother 10 1667-1673
[2]  
Talbot K(2012)Demonstrated brain insulin resistance in Alzheimer's disease patients is associated with IGF-1 resistance, IRS-1 dysregulation, and cognitive decline J Clin Invest 122 1316-1338
[3]  
Wang HY(2005)Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes? J Alzheimers Dis 7 63-80
[4]  
Kazi H(2016)Mechanisms of mitochondrial dysfunction in Alzheimer’s disease Mol Neurobiol 53 6078-6090
[5]  
Han LY(2017)Decreasing body mass index is associated with cerebrospinal fluid markers of Alzheimer's pathology in MCI and mild dementia Exp Gerontol 100 45-53
[6]  
Bakshi KP(2017)Blood-based metabolic signatures in Alzheimer's disease Alzheimers Dement (Amst) 8 196-207
[7]  
Stucky A(2012)Metabolic phenotyping in clinical and surgical environments Nature. 491 384-392
[8]  
Steen E(2016)Emerging applications of metabolomics in drug discovery and precision medicine Nat Rev Drug Discov 15 473-484
[9]  
Terry BM(2012)Innovation: metabolomics: the apogee of the omics trilogy Nat Rev Mol Cell Biol 13 263-269
[10]  
Rivera EJ(2016)Metabolomics: beyond biomarkers and towards mechanisms Nature Reviews Molecular Cell Biology 17 451-459
12345678910