Lack of association between single-nucleotide polymorphisms of pro- and anti-inflammatory cytokines and HTLV-1-associated myelopathy / tropical spastic paraparesis development in patients from Rio de Janeiro, Brazil

被引:0
作者
Doris Schor
Luís Cristóvão Porto
Eric Henrique Roma
Marcel de Souza Borges Quintana
Gustavo Milson Fabricio-Silva
Maria Gloria Bonecini-Almeida
Abelardo Queiroz-Campos Araújo
Maria Jose Andrada-Serpa
机构
[1] Laboratory of Immunology and Immunogenetics in Infectious Diseases,Laboratory for Clinical Research in Neuroinfections
[2] Evandro Chagas National Institute of Infectious Diseases,Histocompatibility and Cryopreservation Laboratory, Policlinica Piquet Carneiro
[3] FIOCRUZ,undefined
[4] Evandro Chagas National Institute of Infectious Diseases,undefined
[5] FIOCRUZ,undefined
[6] Rio de Janeiro State University (UERJ),undefined
[7] Clinical Research Platform,undefined
[8] Evandro Chagas National Institute of Infectious Diseases,undefined
[9] FIOCRUZ,undefined
来源
BMC Infectious Diseases | / 18卷
关键词
Cytokine; HAM/TSP; HTLV-1; SNP; Proviral load;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 197 条
[1]  
Araujo AQC(2006)The HTLV-1 neurological complex Lancet Neurol 5 1068-1076
[2]  
Silva MTT(2012)Clinical pathophysiology of human T-lymphotropic virus-type 1-associated myelopathy/tropical spastic paraparesis Front Microbiol 3 389-1700
[3]  
Yamano Y(2007)Proinflammatory cytokine gene induction by human T-cell leukemia virus type 1 (HTLV-1) and HTLV-2 tax in primary human glial cells J Virol 81 1690-107
[4]  
Sato T(2008)HTLV-1-associated myelopathy/tropical spastic paraparesis (HAM/TSP) inflammatory network Inflamm Allergy Drug Targets 7 98-5609
[5]  
Banerjee P(2008)Dysregulation of TGF-beta signaling and regulatory and effector T-cell function in virus-induced neuroinflammatory disease Blood 111 5601-407
[6]  
Rochford R(2009)The elevated interferon gamma production is an important immunological marker in HAM/TSP pathogenesis Scand J Immunol 70 403-454
[7]  
Antel J(2018)Plasma and cerebrospinal fluid levels of cytokines as disease markers of neurologic manifestation in long-term HTLV-1 infected individuals Biomark Med 12 447-866
[8]  
Canute G(2000)A single nucleotide polymorphism in the first intron of the human IFN-gamma gene: absolute correlation with a polymorphic CA microsatellite marker of high IFN-gamma production Hum Immunol 61 863-399
[9]  
Wrzesinski S(1997)The −308 tumor necrosis factor-alpha promoter polymorphism effects transcription Mol Immunol 34 391-3199
[10]  
Sieburg M(1997)Effects of a polymorphism in the human tumor necrosis factor alpha promoter on transcriptional activation Proc Natl Acad Sci U S A 94 3195-1376