Kinetics of halogen-exchange fluorination of 2,6-dichlorobenzaldehyde

被引：0

作者：

Liang Z. ^{[1
]}

Li B. ^{[1
]}

Lü C. ^{[1
]}

Feng C. ^{[1
]}

机构：

[1] College of Chemical Engineering, Nanjing University of Science and Technology

来源：

Frontiers of Chemical Engineering in China | 2008年 / 2卷 / 1期

关键词：

2,6-dichlorobenzaldehyde; Halogen-exchange fluorination; Kinetics; Phase transfer catalysis;

D O I：

10.1007/s11705-008-0008-1

中图分类号：

学科分类号：

摘要：

Under the conditions of phase transfer catalysis and nitrobenzene as the solvent, the halogen-exchange fluorination of 2,6-dichlorobenzaldehyde using KF as fluorinating agent was studied. The kinetics was investigated and the reaction rate constants were obtained under the optimum conditions of n (KF):n (2,6-dichlorobenzaldehyde): n (Ph4PBr):n(acetone-furan crown ether) = 4:1:0.1:0.05 and temperatures of 433 K, 443 K, 453 K and 463 K. The results illustrated the activation energy of the first and the second step is 4.57 × 104 J·mol-1 and 3.53 × 104 J·mol-1, respectively. The pre-exponential factor is 4.50 × 105 h-1 and 1.08 × 104 h-1, respectively. Thus a reliable kinetics data could be obtained for further research. © Higher Education Press and Springer-Verlag 2008.

引用

页码：59 / 62

页数：3

共 6 条

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