Fabrication of Nontoxic Dye-Embedded Silica Particles for Live Cell Imaging Purposes

被引：10

作者：

Atabaev T.S. ^{[1
]}

Urmanova G. ^{[2
]}

Ajmal M. ^{[3
]}

Hong N.H. ^{[1
]}

机构：

[1] Department of Physics and Astronomy, Seoul National University, Seoul

[2] Department of Biotechnology, National University of Uzbekistan, Tashkent

[3] Institute of Physics and Electronics, University of Peshawar, 2500 Khyber Pakhtunkhwa, Peshawar

来源：

Atabaev, T. S. (atabaev@snu.ac.kr) | 1600年 / Springer Science and Business Media, LLC卷 / 03期

关键词：

Cell imaging; Cytotoxicity; Fluorescence; Silica;

D O I：

10.1007/s12668-013-0082-9

中图分类号：

学科分类号：

摘要：

Fluorescent imaging agents are desirable components for biological imaging applications. Herein, silica particles with strong fluorescent properties have been prepared by Stöber process for live cell imaging purposes. The morphological and chemical properties of synthesized dye-embedded silica particles were characterized by field emission scanning electron microscopy, energy dispersive X-ray, and X-ray photoelectron spectroscopy. Photoluminescence spectroscopy was used to investigate the room temperature fluorescence excitation and emission spectra of synthesized silica particles. It was found that this kind of fluorescent silica particles exhibits a good biocompatibility and a cellular uptake of the probes verified that they maintain well their optical properties within the intracellular environment. © 2013 Springer Science+Business Media New York.

引用

页码：132 / 136

页数：4

共 7 条

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