Angiotensin II subtype AT1 receptor blockade prevents hypertension and renal insufficiency induced by chronic NO-synthase inhibition in rats

被引：0
作者：
M. Hropot
K. H. Langer
Gabriele Wiemer
H. Grötsch
W. Linz
机构：
[1] Aventis Pharma Deutschland GmbH,Cardiovascular Diseases
[2] H 821,undefined
来源：
Naunyn-Schmiedeberg's Archives of Pharmacology | 2003年 / 367卷
关键词：
Fonsartan (HR 720); Losartan; Angiotensin II subtype AT; receptor blocker; NO synthase inhibition; Rat;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Aim of the present study was to investigate the influence of the angiotensin II (ANG II) subtype 1 (AT1) receptor blockers fonsartan and losartan on blood pressure, cardiac -dynamics and -metabolism as well as functional and morphological changes in the kidney of rats after long-term inhibition of the nitric oxide (NO) synthase by NG-nitro-L-arginine methyl ester (L-NAME).
引用
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页码：312 / 317
页数：5
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