Extracellular vesicles derived from different sources of mesenchymal stem cells: therapeutic effects and translational potential

被引：0
作者：
Jiaxin Cai
Junyong Wu
Jiemin Wang
Yongjiang Li
Xiongbin Hu
Shifu Luo
Daxiong Xiang
机构：
[1] Central South University,Department of Pharmacy, The Second Xiangya Hospital
[2] Hunan Provincial Engineering Research Centre of Translational Medicine and Innovative Drug,Institute of Clinical Pharmacy
[3] Central South University,Xiangya School of Pharmaceutical Sciences
[4] Central South University,undefined
来源：
Cell & Bioscience | / 10卷
关键词：
Extracellular vesicles; Exosomes; Mesenchymal stem cells;
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摘要：
Mesenchymal stem cells (MSCs) were known to have excellent properties in cell therapy. However, the risk of immune rejection associated with cell transplant therapy hampers its use. Extracellular vesicles secreted by MSCs derived from different sources that contain therapeutic molecules such as RNA and proteins, which is a novel strategy for cell-free therapy. Recently, researches show EVs from MSCs (MSC-EVs) of different sources have special functions and effects on different diseases. Here, we collected these researches and compared them to each other. In addition, their potential and possible application in clinical treatment are described.
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