Helicobacter pylori May Cause "Reflux" Gastritis after Gastrectomy

被引：7

作者：

Nagahata Y. ^{[1
,2
]}

Azumi Y. ^{[1
]}

Numata N. ^{[1
]}

Yano M. ^{[1
]}

Akimoto T. ^{[1
]}

Saitoh Y. ^{[1
]}

机构：

[1] First Department of Surgery, Kobe University School of Medicine, Kobe

[2] First Department of Surgery, Kobe University School of Medicine, Kobe 650, 7-5-2 Kusunoki-cho, Chuo-ku

来源：

Journal of Gastrointestinal Surgery | 1997年 / 1卷 / 5期

关键词：

Gastritis; Pylorus Infection; Serum Gastrin; Subtotal Gastrectomy; Partial Gastrectomy;

D O I：

10.1016/S1091-255X(97)80137-0

中图分类号：

学科分类号：

摘要：

Patients with "reflux" gastritis after gastrectomy suffer from a variety of symptoms, and this type of gastritis may sometimes compromise the quality of life of these patients. Since Helicobacter pylori is considered to be one of the most important pathogenetic factors in gastritis, the association between H. pylori and reflux gastritis was investigated in this study. A total of 145 patients with gastrectomy were entered into the study. Five biopsy specimens from the gastric remnant were taken at upper gastrointestinal endoscopy. One specimen was examined pathohistologically, and the remaining four were examined for H. pylori infection. Fifty-two patients (36%) demonstrated H. pylori infection. The prevalence of H. pylori was significantly higher in patients who had a partial gastrectomy, and it was significantly lower in patients who had undergone gastrectomy more than 4 years previously. The histologic gastritis score in patients with H. pylori infection was significantly higher. Furthermore, H. pylori was eradicated in patients with some symptoms of gastritis and no bile reflux to the residual stomach at endoscopy; in these patients the symptoms were relieved and the histologic gastritis score decreased significantly. In conclusion, possible involvement of H. pylori is suspected in the pathogenesis of "nonreflux" gastritis after gastrectomy.

引用

页码：479 / 486

页数：7

共 37 条

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