Effect of cilostazol, a selective type-III phosphodiesterase inhibitor, on water-immersion stress-induced gastric mucosal injury in rats

被引:0
作者
Reina Ohba
Michiro Otaka
Masaru Odashima
Mario Jin
Koga Komatsu
Noriaki Konishi
Isao Wada
Youhei Horikawa
Tamotsu Matsuhashi
Jinko Oyake
Natsumi Hatakeyama
Sumio Watanabe
机构
[1] Akita University School of Medicine,Department of Internal Medicine
来源
Journal of Gastroenterology | 2006年 / 41卷
关键词
cilostazol; phosphodiesterase; gastric injury; stress;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:34 / 40
页数:6
相关论文
共 118 条
[11]  
Higuchi K(2004)Cilostazol inhibits high glucose-mediated endothelial-neutrophil adhesion by decreasing adhesion molecule expression via NO production Microvasc Res 68 119-25
[12]  
Tominaga K(1960)A study of the factors involved in the production of gastric ulcers by restraint technique Gastroenterology 38 353-61
[13]  
Fujiwara Y(1976)A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding Anal Biochem 72 248-54
[14]  
Arakawa T(1982)Measurement of cutaneous inflammation: estimation of neutrophil content with the enzyme marker J Invest Dermatol 78 206-9
[15]  
Pacheco I(1984)Quantittative assay for acute intestinal inflammation based on myeloperoxidase activity Gastroenterology 87 1344-50
[16]  
Otaka M(1996)Implication of nitric oxide synthase activity in the genesis of water immersion stress-induced gastric lesions in rats: the protective effects of FK506 Aliment Pharmacol Ther 10 933-40
[17]  
Jin M(2002)Inhibition of lipopolysaccharide-induced apoptosis by cilostazol in human umbilical vein endothelial cells J Pharmacol Exp Ther 300 709-15
[18]  
Komatsu K(2004)The effect of selective phosphodiesterase inhibitors, alone and in combination, on a murine model of allergic asthma Respir Res 5 4-13
[19]  
Odashima M(1994)Adenosine, an endogeneous anti-inflammatory agents J Appl Physiol 76 5-13
[20]  
Watanabe S(1993)Requirements for leukocyte adhesion molecules in nephrotoxic nephritis J Clin Invest 91 577-87