The influence of weak magnetic fields on the production of the reactive oxygen species in peritoneal neutrophils of mice

被引：6

作者：

Belova N.A. ^{[1
]}

Potselueva M.M. ^{[1
]}

Srebnitskaya L.K. ^{[1
]}

Znobishcheva A.V. ^{[1
]}

Lednev V.V. ^{[1
]}

机构：

[1] Institute of Theoretical and Experimental Biophysics, Russian Academy of Sciences, Pushchino

来源：

Biophysics | 2010年 / 55卷 / 4期

关键词：

chemiluminescence; FMLP; magnetic field tuned to the parametric resonance for Ca[!sup]2+[!/sup] ions; neutrophils; phorbol ester; reactive oxygen species;

D O I：

10.1134/S0006350910040123

中图分类号：

学科分类号：

摘要：

The influence of weak magnetic fields of different types on the rate of the formation of reactive oxygen species in mouse peritoneal neutrophils has been studied. It was found that the exposure of neutrophils activated by phorbol 12-myristate 13-acetate to the magnetic field tuned to the parametric resonance for Ca2+ ions leads to a decrease in the rate of the reactive oxygen species (ROS) generation by 23%. Conversely, the generation of ROS in neutrophils exposed to the same field but stimulated by the bacterial peptide FMLP (N-formyl-L-methionyl-L-leucyl-L-phenylalanine) increased by about 21%. Pulsed magnetic fields also changed the rate of ROS generation in phorbol-stimulated neutrophils by about 20%, but the sign of the effects observed in this case was opposite to those induced by the magnetic field tuned to the parametric resonance for Ca2+ ions. © 2010 Pleiades Publishing, Ltd.

引用

页码：586 / 591

页数：5

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