Bmi1 is expressed in vivo in intestinal stem cells

被引:0
|
作者
Eugenio Sangiorgi
Mario R Capecchi
机构
[1] University of Utah School of Medicine,Howard Hughes Medical Institute and Department of Human Genetics
来源
Nature Genetics | 2008年 / 40卷
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摘要
Eugenio Sangiorgi and Mario Capecchi use lineage tracing in mice to identify Bmi1 as a specific marker of a stem cell population located at the +4 position of the small intestinal crypt. Their findings address a long-standing debate in the field and support the existence of two distinct intestinal stem cell populations near the crypt base.
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页码:915 / 920
页数:5
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