Genotype analysis of ORF 62 identifies varicella-zoster virus infections caused by a vaccine strain in children

被引：0
|
作者：
Byung Ok Kwak
Hoan Jong Lee
Hyun Mi Kang
Chi Eun Oh
Eun Hwa Choi
机构：
[1] Seoul National University Children’s Hospital,Division of Pediatric Infectious Diseases, Department of Pediatrics
[2] Konkuk University School of Medicine,Department of Microbiology
[3] Seoul National University College of Medicine,Department of Pediatrics
[4] Kosin University College of Medicine,Department of Pediatrics
来源：
Archives of Virology | 2017年 / 162卷
关键词：
Varicella-zoster virus; Genotype; Children;
D O I：
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中图分类号：
学科分类号：
摘要：
This study was performed to differentiate vaccine-type strains from wild-type strains and determine the genotype of varicella-zoster virus (VZV) in 51 Korean children. A sequencing analysis of ORF 62 identified two cases of herpes zoster caused by the vaccine-type virus, without a previous history of varicella, 22 months and 5 months after VZV vaccination. The wild-type strain was identified in the remaining children. A genotype analysis of ORF 22 amino acids revealed genotype J in all children except one. Genotype E was identified in an infant with varicella imported from Egypt.
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页码：1725 / 1730
页数：5
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