Protocol for a systematic review of N-of-1 trial protocol guidelines and protocol reporting guidelines

[1] Sackett DL(2011)Clinician-trialist rounds: 4. why not do an N-of-1 RCT? Clin Trials 8 350-2

[2] Schork NJ(2015)Personalized medicine: time for one-person trials Nature 520 609-11

[3] Smith LD(2014)N-of-1 genomic medicine for the rare pediatric genetic diseases Expert Opin Orphan Drugs 2 1279-90

[4] Kingsmore SF(1986)Determining optimal therapy—randomized trials in individual patients N Engl J Med 314 889-92

[5] Guyatt G(2009)An N of 1 service: applying the scientific method in clinical practice Scand J Gastroenterol 23 22-9

[6] Sackett D(2013)Experimental designs for small randomised clinical trials: an algorithm for choice Orphanet J of Rare Dis 8 1-1

[7] Taylor DW(2015)CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement BMJ 350 h1738-5

[8] Chong J(2013)N-of-1 trials: individualized medication effectiveness tests AMAJ Ethics 15 42-2

[9] Roberts R(2014)Innovative research methods for studying treatments for rare diseases: methodological review BMJ 349 g6802-3

[10] Pugsley S(2015)CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration BMJ 350 h1793-80

[1] Sackett DL(2011)Clinician-trialist rounds: 4. why not do an N-of-1 RCT? Clin Trials 8 350-2

[2] Schork NJ(2015)Personalized medicine: time for one-person trials Nature 520 609-11

[3] Smith LD(2014)N-of-1 genomic medicine for the rare pediatric genetic diseases Expert Opin Orphan Drugs 2 1279-90

[4] Kingsmore SF(1986)Determining optimal therapy—randomized trials in individual patients N Engl J Med 314 889-92

[5] Guyatt G(2009)An N of 1 service: applying the scientific method in clinical practice Scand J Gastroenterol 23 22-9

[6] Sackett D(2013)Experimental designs for small randomised clinical trials: an algorithm for choice Orphanet J of Rare Dis 8 1-1

[7] Taylor DW(2015)CONSORT extension for reporting N-of-1 trials (CENT) 2015 Statement BMJ 350 h1738-5

[8] Chong J(2013)N-of-1 trials: individualized medication effectiveness tests AMAJ Ethics 15 42-2

[9] Roberts R(2014)Innovative research methods for studying treatments for rare diseases: methodological review BMJ 349 g6802-3

[10] Pugsley S(2015)CONSORT extension for reporting N-of-1 trials (CENT) 2015: explanation and elaboration BMJ 350 h1793-80