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How do statins control neuroinflammation?
被引：0
作者：
P. Adamson
J. Greenwood
机构：
[1] Institute of Ophthalmology,Division of Cell Biology
[2] University College London,undefined
来源：
Inflammation Research
|
2003年
/
52卷
关键词：
Cholesterol;
Atherosclerosis;
Cardiovascular Disease;
Clinical Symptom;
Inflammatory Cell;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Statins are used widely to reduce the levels of low-density lipoproteins and cholesterol and thereby lower the incidence of atherosclerosis and cardiovascular disease. They achieve this through their ability to limit the production of mevalonate via blockade of 3-hydroxy-3-methyl glutaryl coenzyme A (HMG-CoA) reductase. This enzyme is the rate limiting step controlling the de novo production of cholesterol.
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页码：399 / 403
页数：4
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