Extensive review on breast cancer its etiology, progression, prognostic markers, and treatment

被引:0
|
作者
Harshini Swaminathan
K. Saravanamurali
Sangilimuthu Alagar Yadav
机构
[1] Karpagam Academy of Higher Education,Department of Biotechnology
[2] Coimbatore Medical College,Virus Research and Diagnostics Laboratory, Department of Microbiology
来源
Medical Oncology | / 40卷
关键词
Breast cancer; Estrogen receptor; HER2; BRCA1/2; Mammography; Chemotherapy;
D O I
暂无
中图分类号
学科分类号
摘要
As the most frequent and vulnerable malignancy among women, breast cancer universally manifests a formidable healthcare challenge. From a biological and molecular perspective, it is a heterogenous disease and is stratified based on the etiological factors driving breast carcinogenesis. Notably, genetic predispositions and epigenetic impacts often constitute the heterogeneity of this disease. Typically, breast cancer is classified intrinsically into histological subtypes in clinical landscapes. These stratifications empower physicians to tailor precise treatments among the spectrum of breast cancer therapeutics. In this pursuit, numerous prognostic algorithms are extensively characterized, drastically changing how breast cancer is portrayed. Therefore, it is a basic requisite to comprehend the multidisciplinary rationales of breast cancer to assist the evolution of novel therapeutic strategies. This review aims at highlighting the molecular and genetic grounds of cancer additionally with therapeutic and phytotherapeutic context. Substantially, it also renders researchers with an insight into the breast cancer cell lines as a model paradigm for breast cancer research interventions.
引用
收藏
相关论文
共 50 条
  • [31] Review of hormonal treatment of breast cancer
    Abdulkareem, I. H.
    Zurmi, I. B.
    NIGERIAN JOURNAL OF CLINICAL PRACTICE, 2012, 15 (01) : 9 - 14
  • [32] Prognostic value of proliferation markers expression in breast cancer
    Natalija Dedić Plavetić
    Jasminka Jakić-Razumović
    Ana Kulić
    Damir Vrbanec
    Medical Oncology, 2013, 30
  • [33] MicroRNAs 182 and 375 Sera Expression as Prognostic Biochemical Markers in Breast Cancer
    Ali, Ola S.
    Shabayek, Marwa, I
    Seleem, Mae M.
    Abdellateif, Heba G.
    Makhlouf, Dalia O.
    CLINICAL BREAST CANCER, 2018, 18 (06) : E1373 - E1379
  • [34] MGMT and PTEN as potential prognostic markers in breast cancer
    Neto, Julio Cirullo
    Ikoma, Mariana Mari
    Carvalho, Katia Candido
    Vassallo, Jose
    De Brot, Marina
    Gobbi, Helenice
    Soares, Fernando Augusto
    Rocha, Rafael Malagoli
    EXPERIMENTAL AND MOLECULAR PATHOLOGY, 2012, 92 (01) : 20 - 26
  • [35] Predictive and prognostic markers in breast cancer treatment - Presentations at the 28th San Antonio Breast Cancer Symposium 2005
    Rody, Achim
    Karn, Thomas
    Kaufmann, Manfred
    BREAST CARE, 2006, 1 (02) : 118 - 122
  • [36] Importance of MACC1 expression in breast cancer and its relationship with pathological prognostic markers
    Soyleyici, Nevroz A.
    Aslan, Figen
    Avcikurt, Ayla S.
    Akgun, Gizem A.
    INDIAN JOURNAL OF PATHOLOGY AND MICROBIOLOGY, 2020, 63 (01) : 19 - 24
  • [37] Advances in Analyzing the Breast Cancer Lipidome and Its Relevance to Disease Progression and Treatment
    Ashley V. Ward
    Steven M. Anderson
    Carol A. Sartorius
    Journal of Mammary Gland Biology and Neoplasia, 2021, 26 : 399 - 417
  • [38] CELL BIOLOGICAL PROGNOSTIC FACTORS IN BREAST-CANCER - A REVIEW
    FOEKENS, JA
    PETERS, HA
    PORTENGEN, H
    NOORDEGRAAF, E
    BERNS, EMJJ
    KLIJN, JGM
    JOURNAL OF CLINICAL IMMUNOASSAY, 1991, 14 (03): : 184 - 195
  • [39] Possibilities of a viral etiology for human breast cancer - A review
    Pogo, BGT
    Holland, JF
    BIOLOGICAL TRACE ELEMENT RESEARCH, 1997, 56 (01) : 131 - 142
  • [40] Advances in Analyzing the Breast Cancer Lipidome and Its Relevance to Disease Progression and Treatment
    Ward, Ashley V.
    Anderson, Steven M.
    Sartorius, Carol A.
    JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA, 2021, 26 (04) : 399 - 417