Biomarkers in Traumatic Brain Injury

被引:0
作者
Richa Sharma
Daniel T. Laskowitz
机构
[1] Duke University Medical Center,School of Medicine
[2] Duke University Medical Center,Department of Medicine (Neurology)
来源
Current Neurology and Neuroscience Reports | 2012年 / 12卷
关键词
Traumatic brain injury; Biomarkers; Glasgow Coma Score; S100B; GFAP; NSE; Alpha II spectrin; End-of-life decisions; Clinical trials; Diffuse axonal injury; Hematoma; Concussion; Inflammation;
D O I
暂无
中图分类号
学科分类号
摘要
Traumatic brain injury (TBI) is a common cause of neurological morbidity globally, and neurologic sequelae may occur even in the setting of mild injury. At present, the tools that guide diagnostic and prognostic evaluation of patients who suffer from TBI remain limited, especially for prehospital evaluation. Biomarkers of brain injury hold promise in facilitating early management and triage decisions in the civilian and military settings. The identification of biomarkers of brain injury may also be helpful in guiding end-of-life decision making and may facilitate the design of neuroprotective trials.
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页码:560 / 569
页数:9
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