Pharmacological investigations of organic crude fractions of Dysophylla auricularia

被引：5
作者：
Nur T. [1 ]
Islam M.T. [1 ,4 ]
Alam S. [2 ]
Chowdhury M.M.U. [1 ]
Melo-Cavalcante A.A.C. [3 ]
de Freitas R.M. [4 ]
机构：
[1] Department of Pharmacy, Southern University Bangladesh, 22-Shahid Mirza Lane (E), Academic Building-II, 739/A, Mehedibag Road, Mehedibag-4000, Chittagong
[2] Forest Botany Division, Bangladesh Forest Reseach Institute, Chittagong
[3] Laboratory of Research in Genetic Toxicology, Post-Graduation Program in Pharmaceutics Science, Federal University of Piauí, Teresina, 64.049-550, Piauí
[4] Laboratory of Research in Experimental Neurochemistry, Post-Graduation Program in Pharmaceutics Science, Federal University of Piauí, Teresina, 64.049-550, Piauí
来源：
Oriental Pharmacy and Experimental Medicine | 2015年 / 15卷 / 3期
关键词：
Crude; Dysophylla auricularia; Organic fractions; Pharmacological;
D O I：
10.1007/s13596-015-0190-x
中图分类号：
学科分类号：
摘要：
The aim of this present study is to investigate pharmacological activities of organic crude fractions of Dysophylla auricularia. For this organic fractions namely - ethanol, chloroform and n-hexane have been investigated for antimicrobial, anti-diarrheal, anti-inflammatory and membrane stabilization, α-glycosidase inhibitory and antipyretic activities. Results suggest that in the antimicrobial sensitivity study, ethanol and chloroform fractions produced inhibition zones with the ranges of 12 to 20 mm and 7 to 21 mm, respectively; where they strongly inhibited the growth of Shigella sonnei, Escherichia coli, Shigella dysenteriae and Microsporum sp. Crude fractions also revealed the presence of antidiarrheal, antiinflammatory and membrane stabilization, anti-amylase as well as antipyretic activities. In conclusion, it should be mentioned that D. auricularia may have one of the good sources for phytotherapy. © 2015, Institute of Korean Medicine, Kyung Hee University and Springer Science+Business Media Dordrecht.
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收藏
页码：207 / 215
页数：8
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