Physicochemical Properties and Methods for the Determination of Metformin Hydrochloride (A Review)

被引：0
作者：
E. B. Polyakova
D. R. Sabirzyanov
N. A. Prozorova
A. B. Foteeva
机构：
[1] Parma Clinical LLC,
[2] Perm State Pharmaceutical Academy,undefined
来源：
Pharmaceutical Chemistry Journal | 2022年 / 55卷
关键词：
metformin hydrochloride; biguanides; physicochemical properties; methods of analysis; antidiabetic drugs; medicinal substances;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
Metformin hydrochloride is widely used to treat diabetes mellitus. This review presents its physical and chemical properties and discusses methods of analysis that allow a quality assessment of metformin hydrochloride both as an individual drug and in combination with other antidiabetic medicines. The most widely used method is HPLC combined with spectrophotometry and other methods of analysis. The review is based on data from foreign and domestic articles and on our research results.
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页码：1119 / 1125
页数：6
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