Alternative splicing and genome complexity

被引：0
|
作者：
David Brett
Heike Pospisil
Juan Valcárcel
Jens Reich
Peer Bork
机构：
[1] Max Delbrück Center for Molecular Medicine,
[2] European Molecular Biology Laboratory,undefined
来源：
Nature Genetics | 2002年 / 30卷
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摘要：
Alternative splicing of mRNA allows many gene products with different functions to be produced from a single coding sequence. It has recently been proposed as a mechanism by which higher-order diversity is generated. Here we show, using large-scale expressed sequence tag (EST) analysis, that among seven different eukaryotes the amount of alternative splicing is comparable, with no large differences between humans and other animals.
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页码：29 / 30
页数：1
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