Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α

被引：0
作者：
Ivan D Mascanfroni
Maisa C Takenaka
Ada Yeste
Bonny Patel
Yan Wu
Jessica E Kenison
Shafiuddin Siddiqui
Alexandre S Basso
Leo E Otterbein
Drew M Pardoll
Fan Pan
Avner Priel
Clary B Clish
Simon C Robson
Francisco J Quintana
机构：
[1] Center for Neurologic Diseases,Division of Gastroenterology
[2] Brigham and Women's Hospital,Department of Microbiology
[3] Harvard Medical School,Immunology and Hematopoiesis Division, Department of Oncology and Medicine
[4] Hepatology and Transplantation,Department of Physics
[5] Beth Israel Deaconess Medical Center,undefined
[6] Harvard Medical School,undefined
[7] Immunology and Parasitology,undefined
[8] Escola Paulista de Medicina,undefined
[9] Federal University of São Paulo,undefined
[10] Johns Hopkins University School of Medicine,undefined
[11] University of Alberta,undefined
[12] Center for Proteomics,undefined
[13] The Broad Institute of Massachusetts Institute of Technology (MIT) and Harvard,undefined
来源：
Nature Medicine | 2015年 / 21卷
关键词：
D O I：
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中图分类号：
学科分类号：
摘要：
Metabolic changes induced by hypoxia and extracellular ATP, acting through the transcription factors HIF1-α and AHR, regulate the differentiation of type 1 regulatory (Treg1) cells.
引用
收藏
页码：638 / 646
页数：8
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