Hemangioma of the mandible: Case report with special emphasis on bone degradation

被引：5

作者：

Hansen T. ^{[1
]}

Kunkel M. ^{[2
]}

Katenkamp D. ^{[3
]}

Eletr S. ^{[4
]}

Wagner W. ^{[4
]}

机构：

[1] Institute of Pathology, Johannes Gutenberg University of Mainz, Mainz 55101

[2] Department of Oral and Maxillofacial Surgery, University of Bochum, Bochum

[3] Institute of Pathology, Friedrich Schiller University of Jena, Jena

[4] Department of Oral and Maxillofacial Surgery, Johannes Gutenberg University of Mainz, Mainz

来源：

Oral and Maxillofacial Surgery | 2009年 / 13卷 / 4期

关键词：

Angiogenesis; Bone degradation; Hemangioma; Mandible; Osteoclast;

D O I：

10.1007/s10006-009-0172-6

中图分类号：

学科分类号：

摘要：

Purpose: Intraosseous hemangioma of the mandible is a rare tumor. In this report, we present a case with a particularly prominent osteolysis and discuss the histological features of bone degradation. Materials and methods: We describe a 64-year-old female patient with a cystic tumor mass of the mandible leading to pathologic bone fracture. X-ray analysis was suggestive for aneurysmatic bone cyst. A segment resection was performed. Results: The histological examination revealed a mesenchymal tumor with numerous capillaries and dilated vessels immunohistochemically being positive for CD31, but not for D2-40. In addition, there was a remarkable increase of osteoclasts that sometimes exhibited Howship's lacunae. The tumor was diagnosed as intraosseous hemangioma with prominent bone degradation. Conclusions: Based on our histological findings, it should be further investigated whether there could be an association between angiogenesis and osteoclastogenesis as a central pathway leading to bone destruction in the case of intraosseous hemangiomas. © 2009 Springer-Verlag.

引用

页码：239 / 242

页数：3

共 15 条

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