Microglia-induced autophagic death of neurons via IL-6/STAT3/miR-30d signaling following hypoxia/ischemia

被引:0
作者
Jun Shu
Xu-Hao Fang
Ya-Jian Li
Yao Deng
Wen-Shi Wei
Li Zhang
机构
[1] Fudan University,Department of Neurology, Huadong Hospital
[2] Fudan University,Stroke Center, Huadong Hospital
[3] Fudan University,Department of Neurosurgery, Huadong Hospital
[4] Fudan University,Department of Neurology, Stroke Center, Huadong Hospital
来源
Molecular Biology Reports | 2022年 / 49卷
关键词
Microglial activation; Neuronal apoptosis; Autophagy; IL-6;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:7697 / 7707
页数:10
相关论文
共 123 条
[31]  
Katuri A(2018)miR-23b improves cognitive impairments in traumatic brain injury by targeting ATG12-mediated neuronal autophagy Behav Brain Res 340 126-undefined
[32]  
Bryant J(2021)Microglial metabolic disturbances and neuroinflammation in cerebral infarction J Pharmacol Sci 145 130-undefined
[33]  
Heredia A(2012)The classification of microglial activation phenotypes on neurodegeneration and regeneration in Alzheimer’s disease brain Arch Immunol Ther Exp (Warsz) 60 251-undefined
[34]  
Kwon HS(2019)MiR-181b inhibits P38/JNK signaling pathway to attenuate autophagy and apoptosis in juvenile rats with kainic acid-induced epilepsy via targeting TLR4 CNS Neurosci Ther 25 112-undefined
[35]  
Koh SH(2013)MicroRNA 23b regulates autophagy associated with radioresistance of pancreatic cancer cells Gastroenterology 145 1133-undefined
[36]  
Lana D(2021)An updated review of autophagy in ischemic stroke: From mechanisms to therapies Exp Neurol 340 113684-undefined
[37]  
Ugolini F(2018)Overexpression of miR185 inhibits autophagy and apoptosis of dopaminergic neurons by regulating the AMPK/mTOR signaling pathway in Parkinson’s disease Mol Med Rep 17 131-undefined
[38]  
Giovannini MG(2021)Orexin-A protects against cerebral ischemia-reperfusion injury by inhibiting excessive autophagy through OX1R-mediated MAPK/ERK/mTOR pathway Cell Signal 79 109839-undefined
[39]  
Lekanne Deprez RH(2012)The microRNA miR-181c controls microglia-mediated neuronal apoptosis by suppressing tumor necrosis factor J Neuroinflammation 9 211-undefined
[40]  
Fijnvandraat AC(2012)miR-21 represses FasL in microglia and protects against microglia-mediated neuronal cell death following hypoxia/ischemia Glia 60 1888-undefined