Medication Adherence Mediates the Relationship between Adherence Self-efficacy and Biological Assessments of HIV Health among those with Alcohol Use Disorders

被引:0
作者
Jeffrey T. Parsons
Elana Rosof
Brian Mustanski
机构
[1] Hunter College of the City University of New York,Department of Psychology
[2] Center for HIV/AIDS Educational Studies and Training (CHEST),undefined
[3] Center for HIV/AIDS Educational Studies and Training (CHEST),undefined
[4] Medical and Health Research Association of NYC,undefined
[5] Inc,undefined
[6] University of Illinois,undefined
来源
AIDS and Behavior | 2008年 / 12卷
关键词
Adherence; Alcohol; Self-efficacy; Viral load; CD4;
D O I
暂无
中图分类号
学科分类号
摘要
The current study examines the relationship between negative consequences of alcohol use, adherence self-efficacy, medication adherence, and biological markers of HIV health (CD4 count and viral load). A total of 275 HIV-positive men and women with alcohol use disorders were surveyed using Audio-CASI measures and time line followback interviews. Findings from a structural equation model suggest that negative consequences related to alcohol use did not directly impact HIV health. Adherence self-efficacy had direct effects on viral load, but not CD4 count. Mediation analyses indicated that self-reported adherence partially mediated the relationship between adherence self-efficacy and viral load. Cognitive-oriented interventions aimed at facilitating adherence self-efficacy may be effective in improving both medication adherence and HIV health. If facilitating confidence improves HIV health, then health care providers can make a strong impact by spending a few short minutes themselves and/or partnering with behavioral health clinicians using techniques like motivational enhancement.
引用
收藏
页码:95 / 103
页数:8
相关论文
共 200 条
  • [1] Ammassari A.(2001)Self-reported symptoms and medication side effects influence adherence to highly active antiretroviral therapy in persons with HIV infection Journal of Acquired Immune Deficiency Syndromes 28 445-449
  • [2] Murri R.(2002)Correlates and predictors of adherence to highly active antiretroviral therapy: Overview of published literature Journal of Acquired Immune Deficiency Syndromes 31 S123-S127
  • [3] Pezzotti P.(1986)Prediction of goal-directed behavior: Attitudes, intentions and perceived behavioral control Journal of Experimental Social Psychology 22 453-474
  • [4] Trotta M. P.(1993)Alcohol intake increases human immunodeficiency virus type 1 replication in human peripheral blood mononuclear cells Journal of Infectious Diseases 167 789-797
  • [5] Ravasio L.(2003)The effect of chronic binge ethanol consumption on the primary stage of SIV infection in rhesus macaques Alcoholism Clinical and Experimental Research 27 495-502
  • [6] De Longis P.(2001)Non-adherence to highly active antiretroviral therapy predicts progression to AIDS AIDS 15 1181-1183
  • [7] Ammassari A.(1995)The Alcohol Use Disorders Identification Test (AUDIT): Validation of a screening instrument for use in medical settings Journal of Studies on Alcohol 56 423-432
  • [8] Trotta M. P.(2007)Mediational analysis in HIV/AIDS research: Estimating multivariate path analytic models in a structural equation modeling framework AIDS & Behavior 11 365-383
  • [9] Murri R.(2005)Condom use among high-risk adolescents: Testing the influence of alcohol use on the relationship of cognitive correlates of behavior Health Psychology 24 133-142
  • [10] Castelli F.(2001)Impaired response to HAART in HIV-infected individuals with high autonomic nervous system activity Proceedings of the National Academy of Science 98 12695-12700