Significant correlation between LKB1 and LGR5 gene expression and the association with poor recurrence-free survival in rectal cancer after preoperative chemoradiotherapy

[11] Shen J(2009)Wnt signaling, lgr5, and stem cells in the intestine and skin Am J Pathol 174 715-721

[12] Person MD(2011)Liver kinase B1 (LKB1) in the pathogenesis of epithelial cancers Cancer Lett 306 1-9

[13] Kusewitt D(2006)Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis Gut 55 1-5

[14] Mills GB(2009)LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism Physiol Rev 89 777-798

[15] Kastan MB(2011)Elevation of WNT5A expression in polyp formation in Lkb1 ± mice and Peutz-Jeghers syndrome J Pathol 223 584-592

[16] Walker CL(2010)Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression Oncol Rep 23 1569-1576

[17] Barcellos-Hoff MH(2011)The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse Cell Stem Cell 8 511-524

[18] Park C(2010)Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells Nature 468 653-658

[19] Wright EG(2011)Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type Cancer Cell 19 640-651

[20] Barker N(2005)Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer Histopathology 47 141-146

[11] Shen J(2009)Wnt signaling, lgr5, and stem cells in the intestine and skin Am J Pathol 174 715-721

[12] Person MD(2011)Liver kinase B1 (LKB1) in the pathogenesis of epithelial cancers Cancer Lett 306 1-9

[13] Kusewitt D(2006)Mucosal prolapse in the pathogenesis of Peutz-Jeghers polyposis Gut 55 1-5

[14] Mills GB(2009)LKB1 and AMPK family signaling: the intimate link between cell polarity and energy metabolism Physiol Rev 89 777-798

[15] Kastan MB(2011)Elevation of WNT5A expression in polyp formation in Lkb1 ± mice and Peutz-Jeghers syndrome J Pathol 223 584-592

[16] Walker CL(2010)Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression Oncol Rep 23 1569-1576

[17] Barcellos-Hoff MH(2011)The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse Cell Stem Cell 8 511-524

[18] Park C(2010)Lkb1 regulates cell cycle and energy metabolism in haematopoietic stem cells Nature 468 653-658

[19] Wright EG(2011)Radiation acts on the microenvironment to affect breast carcinogenesis by distinct mechanisms that decrease cancer latency and affect tumor type Cancer Cell 19 640-651

[20] Barker N(2005)Pathological response following long-course neoadjuvant chemoradiotherapy for locally advanced rectal cancer Histopathology 47 141-146