Chimeric Antigen Receptor–Modified T Cells and T Cell–Engaging Bispecific Antibodies: Different Tools for the Same Job

被引：0
作者：
Melanie Schwerdtfeger
Mohamed-Reda Benmebarek
Stefan Endres
Marion Subklewe
Vincenzo Desiderio
Sebastian Kobold
机构：
[1] LMU Munich,Center of Integrated Protein Science Munich (CIPS
[2] University of Campania “Luigi Vanvitelli”,M) and Division of Clinical Pharmacology, Department of Medicine IV, Klinikum der Universität München
[3] German Center for Translational Cancer Research (DKTK),Department of Experimental Medicine
[4] German Research Center for Environmental Health (HMGU),Einheit für Klinische Pharmakologie (EKLiP), Helmholtz Zentrum München
[5] LMU Munich,Department of Medicine III, Klinikum der Universität München
来源：
Current Hematologic Malignancy Reports | 2021年 / 16卷
关键词：
Chimeric antigen receptor; Bispecific antibody; Immunotherapy; Adoptive T cell therapy; T cell redirection; Cancer;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
页码：218 / 233
页数：15
相关论文
共 50 条
[21]   Chimeric antigen receptor T-cell therapy in glioblastoma: charging the T cells to fight [J].
Land, Craig A. ;
Musich, Phillip R. ;
Haydar, Dalia ;
Krenciute, Giedre ;
Xie, Qian .
JOURNAL OF TRANSLATIONAL MEDICINE, 2020, 18 (01)
[22]   Manufacturability and functionality assessment of different formats of T-cell engaging bispecific antibodies [J].
Loh, Han Ping ;
Mahfut, Farouq Bin ;
Chen, Serene W. ;
Huang, Yuhan ;
Huo, Jianxin ;
Zhang, Wei ;
Lam, Kong Peng ;
Xu, Shengli ;
Yang, Yuansheng .
MABS, 2023, 15 (01)
[23]   Chimeric antigen receptor T-cell therapy for T-ALL and AML [J].
Wei, Wenwen ;
Yang, Dong ;
Chen, Xi ;
Liang, Dandan ;
Zou, Liqun ;
Zhao, Xudong .
FRONTIERS IN ONCOLOGY, 2022, 12
[24]   How to train your T cell: genetically engineered chimeric antigen receptor T cells versus bispecific T-cell engagers to target CD19 in B acute lymphoblastic leukemia [J].
Ruella, Marco ;
Gill, Saar .
EXPERT OPINION ON BIOLOGICAL THERAPY, 2015, 15 (06) :761-766
[25]   Chimeric antigen receptor-modified T cells strike back [J].
Frigault, Matthew J. ;
Maus, Marcela V. .
INTERNATIONAL IMMUNOLOGY, 2016, 28 (07) :355-363
[26]   The road ahead for chimeric antigen receptor T cells [J].
Stewart, Carli M. ;
Siegler, Elizabeth L. ;
Kenderian, Saad S. .
JOURNAL OF IMMUNOLOGY, 2025, 214 (07) :1457-1467
[27]   Chimeric Antigen Receptor T Cells Targeting Integrin αvβ6 Expressed on Cholangiocarcinoma Cells [J].
Phanthaphol, Nattaporn ;
Somboonpatarakun, Chalermchai ;
Suwanchiwasiri, Kwanpirom ;
Chieochansin, Thaweesak ;
Sujjitjoon, Jatuporn ;
Wongkham, Sopit ;
Maher, John ;
Junking, Mutita ;
Yenchitsomanus, Pa-thai .
FRONTIERS IN ONCOLOGY, 2021, 11
[28]   Chimeric antigen receptor T cell: A cancer immunotherapy [J].
Singh, Surjit ;
Khasbage, Sameer ;
Kaur, Rimple Jeet ;
Sidhu, Jaspreet Kaur ;
Bhandari, Bharti .
INDIAN JOURNAL OF PHARMACOLOGY, 2022, 54 (03) :226-233
[29]   T-cell Immunotherapy and Cardiovascular Disease Chimeric Antigen Receptor T-cell and Bispecific T-cell Engager Therapies [J].
Stein-Merlob, Ashley F. ;
Ganatra, Sarju ;
Yang, Eric H. .
HEART FAILURE CLINICS, 2022, 18 (03) :443-454
[30]   Expanding the Therapeutic Reach of Chimeric Antigen Receptor T-Cells and Bispecific T-Cell Engagers Across Solid Tumors [J].
Gerber, William K. ;
Xie, Yiyu ;
Patel, Shyam A. .
JCO PRECISION ONCOLOGY, 2025, 9
12345