Synthesis and physicochemical properties of the pectin complexes with Xymedon

被引:0
作者
S. T. Minzanova
V. F. Mironov
A. V. Khabibullina
D. M. Arkhipova
L. G. Mironova
I. S. Ryzhkina
S. Yu. Sergeeva
L. I. Murtazina
F. R. Smolobochkina
V. A. Milyukov
机构
[1] Federal Research Center “Kazan Scientific Center of the Russian Academy of Sciences,A. E. Arbuzov Institute of Organic and Physical Chemistry
[2] ”,undefined
来源
Russian Chemical Bulletin | 2019年 / 68卷
关键词
pectin; Xymedon; complexation;
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学科分类号
摘要
The formation of stable complexes of pectin polysaccharides with 1-(2-hydroxyethyl)-4,6- dimethyl-1,2-dihydropyrimidin-2-one (Xymedon drug) was shown by UV and IR spectro scopy, dynamic light scattering, and polarimetry. The stoichiometry of the complexes was determined, and their synthesis conditions were optimized. Specific features of the thermal decomposition of pectin and synthesized complexes with Xymedon were studied by the TG/DSC method. The results obtained allow one to substantially extend ranges of using Xymedon in medicine.
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页码:405 / 410
页数:5
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