Can cell therapy heal a spinal cord injury?

被引:0
作者
M W Ronsyn
Z N Berneman
V F I Van Tendeloo
P G Jorens
P Ponsaerts
机构
[1] University of Antwerp,Division of Clinical Pharmacotherapy
[2] Centre for Cell Therapy and Regenerative Medicine,undefined
[3] Antwerp University Hospital,undefined
[4] University of Antwerp,undefined
[5] Laboratory of Experimental Hematology,undefined
[6] Vaccine and Infectious Disease Institute (VIDI),undefined
[7] University of Antwerp,undefined
来源
Spinal Cord | 2008年 / 46卷
关键词
spinal cord injury; cell transplantation; neurotrophic factors; endogenous neural regeneration; inflammation; clinical trials;
D O I
暂无
中图分类号
学科分类号
摘要
引用
收藏
页码:532 / 539
页数:7
相关论文
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[1]  
Wyndaele M(2006)Incidence, prevalence and epidemiology of spinal cord injury: what learns a worldwide literature survey? Spinal Cord 44 523-529
[2]  
Wyndaele JJ(1990)A randomized, controlled trial of methylprednisolone or naloxone in the treatment of acute spinal-cord injury. Results of the Second National Acute Spinal Cord Injury Study N Engl J Med 322 1405-1411
[3]  
Bracken MB(2000)Direct isolation of human central nervous system stem cells Proc Natl Acad Sci USA 97 14720-14725
[4]  
Shepard MJ(1999)Transplanted embryonic stem cells survive, differentiate and promote recovery in injured rat spinal cord Nat Med 5 1410-1412
[5]  
Collins WF(2007)Embryonic stem cell transplantation after experimental traumatic brain injury dramatically improves neurological outcome, but may cause tumors J Neurotrauma 24 216-225
[6]  
Holford TR(2001)Transplantation of clonal neural precursor cells derived from adult human brain establishes functional peripheral myelin in the rat spinal cord Exp Neurol 167 27-39
[7]  
Young W(2002)Functional recovery following traumatic spinal cord injury mediated by a unique polymer scaffold seeded with neural stem cells Proc Natl Acad Sci USA 99 3024-3029
[8]  
Baskin DS(2001)Axonal regeneration and functional recovery after complete spinal cord transection in rats by delayed treatment with transplants and neurotrophins J Neurosci 21 9334-9344
[9]  
Uchida N(2001)Conduction of impulses by axons regenerated in a Schwann cell graft in the transected adult rat thoracic spinal cord J Neurosci Res 64 533-541
[10]  
Buck DW(2002)Pluripotency of mesenchymal stem cells derived from adult marrow Nature 418 41-49