The role of extracellular vesicles in COPD and potential clinical value

被引：0
作者：
Shasha Liu
Xiaowu Tan
Sha Liu
机构：
[1] University of South China,Department of Pulmonary and Critical Care Medicine, The Second Affiliated Hospital, Hengyang Medical School
来源：
Respiratory Research | / 25卷
关键词：
Extracellular vesicles; Chronic obstructive pulmonary disease; Pathogenesis; Biomarkers; Clinical application;
D O I：
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摘要：
Chronic obstructive pulmonary disease (COPD) is a heterogeneous lung disease and a major health burden worldwide. Extracellular vesicles (EVs) are nanosized vesicles which possess a lipid bilayer structure that are secreted by various cells. They contain a variety of bioactive substances, which can regulate various physiological and pathological processes and are closely related to the development of diseases. Recently, EVs have emerged as a novel tool for intercellular crosstalk, which plays an essential role in COPD development. This paper reviews the role of EVs in the development of COPD and their potential clinical value, in order to provide a reference for further research on COPD.
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